GALENA BIOPHARMA, INC., 10-Q filed on 11/13/2012
Quarterly Report
Document and Entity Information
9 Months Ended
Sep. 30, 2012
Nov. 7, 2012
Entity Information [Line Items]
 
 
Document Type
10-Q 
 
Amendment Flag
false 
 
Document Period End Date
Sep. 30, 2012 
 
Document Fiscal Year Focus
2012 
 
Document Fiscal Period Focus
Q3 
 
Trading Symbol
GALE 
 
Entity Registrant Name
Galena Biopharma, Inc. 
 
Entity Central Index Key
0001390478 
 
Current Fiscal Year End Date
--12-31 
 
Entity Filer Category
Smaller Reporting Company 
 
Entity Common Stock, Shares Outstanding
 
67,627,320 
Condensed Consolidated Balance Sheets (USD $)
In Thousands, unless otherwise specified
Sep. 30, 2012
Dec. 31, 2011
Current assets:
 
 
Cash and cash equivalents
$ 15,423 
$ 11,433 
Restricted cash
101 
101 
Prepaid expenses
801 
276 
Total current assets
16,325 
11,810 
Equipment and furnishings, net
31 
393 
In-process research and development
12,864 
12,864 
Goodwill
5,898 
5,898 
Deposits
74 
Total assets
35,192 
30,968 
Current liabilities:
 
 
Accounts payable
2,210 
2,155 
Accrued expenses and other current liabilities
2,012 
2,984 
Current maturities of capital lease obligations
35 
Convertible notes payable
 
500 
Fair value of warrants potentially settleable in cash
4,904 
3,746 
Current contingent purchase price consideration
925 
1,782 
Total current liabilities
10,057 
11,202 
Capital lease obligations, net of current maturities
51 
32 
Deferred tax liability, non-current
5,053 
5,053 
Contingent purchase price consideration, net of current portion
5,866 
4,569 
Total liabilities
21,027 
20,856 
Commitments and contingencies (Note 8)
   
   
Stockholders' equity:
 
 
Preferred stock, $0.0001 par value; 5,000,000 shares authorized; no shares issued and outstanding
Common stock, $0.0001 par value; 125,000,000 shares authorized; 68,278,653 shares issued and 67,603,653 shares outstanding and 47,811,453 shares issued and 47,136,453 outstanding at September 30, 2012 and December 31, 2011, respectively
Additional paid-in capital
116,453 
81,184 
Deficit accumulated during the developmental stage
(98,446)
(67,228)
Less treasury shares at cost, 675,000 shares
(3,849)
(3,849)
Total stockholders' equity
14,165 
10,112 
Total liabilities and stockholders' equity
$ 35,192 
$ 30,968 
Condensed Consolidated Balance Sheets (Parenthetical) (USD $)
Sep. 30, 2012
Dec. 31, 2011
Preferred stock, par value
$ 0.0001 
$ 0.0001 
Preferred stock, shares authorized
5,000,000 
5,000,000 
Preferred stock, shares issued
   
   
Preferred stock, shares outstanding
   
   
Common stock, par value
$ 0.0001 
$ 0.0001 
Common stock, shares authorized
125,000,000 
125,000,000 
Common stock, shares issued
68,278,653 
47,811,453 
Common stock, shares outstanding
67,603,653 
47,136,453 
Treasury stock, shares
675,000 
675,000 
Condensed Consolidated Statements Of Expenses (USD $)
In Thousands, except Per Share data, unless otherwise specified
3 Months Ended 9 Months Ended 108 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Expenses:
 
 
 
 
 
Research and development expense
$ 4,074 
$ 1,332 
$ 10,168 
$ 1,798 
$ 15,144 
Research and development employee stock-based compensation expense
48 
 
138 
 
347 
Research and development non-employee stock-based compensation expense
47 
35 
197 
(41)
6,189 
Fair value of common stock issued in exchange for research and development services
 
 
50 
 
50 
Total research and development expense
4,169 
1,367 
10,553 
1,757 
21,730 
General and administrative expense
1,090 
1,441 
4,137 
4,972 
31,496 
General and administrative employee stock-based compensation expense
85 
608 
366 
2,035 
9,956 
Fair value of common stock warrants issued for general and administrative services
96 
19 
342 
106 
2,744 
Fair value of common stock issued in exchange for general and administrative expense
88 
 
223 
23 
577 
Total general and administrative expense
1,359 
2,068 
5,068 
7,136 
44,773 
Operating loss
(5,528)
(3,435)
(15,621)
(8,893)
(66,503)
Interest income (expense)
 
(2)
(35)
(6)
587 
Other income (expense) (Note 1)
(733)
(397)
(13,918)
1,723 
(1,859)
Loss from continuing operations
(6,261)
(3,834)
(29,574)
(7,176)
(67,775)
Loss from discontinued operations
 
(1,641)
(1,644)
(5,898)
(40,711)
Net loss
$ (6,261)
$ (5,475)
$ (31,218)
$ (13,074)
$ (108,486)
Net loss per common share:
 
 
 
 
 
Basic and diluted loss per share, continuing operations
$ (0.09)
$ (0.09)
$ (0.49)
$ (0.21)
 
Basic and diluted loss per share, discontinued operations
 
$ (0.04)
$ (0.03)
$ (0.18)
 
Basic and diluted net loss per share
$ (0.09)
$ (0.13)
$ (0.52)
$ (0.39)
 
Weighted average common shares outstanding-basic and diluted
67,265,470 
41,970,481 
60,150,658 
33,697,704 
 
Condensed Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
9 Months Ended 117 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Cash flows from operating activities:
 
 
 
Net loss
$ (31,218)
$ (13,074)
$ (108,486)
Adjustments to reconcile net loss to net cash used in operating activities:
 
 
 
Depreciation and amortization expense
47 
126 
711 
Loss on disposal of equipment
 
19 
Non-cash rent expense
 
 
29 
Accretion and receipt of bond discount
 
 
35 
Non-cash share-based compensation
801 
2,801 
19,659 
Change in fair value of shares mandatorily redeemable for cash upon exercise of warrants
 
 
(785)
Fair value of common stock warrants issued in exchange for services
342 
106 
2,744 
Fair value of common stock issued in exchange for services
267 
23 
627 
Change in fair value of common stock warrants issued in equity financings
11,899 
(1,042)
721 
Fair value of common stock issued in exchange for licensing rights
 
 
3,954 
Change in fair value of contingent purchase consideration
2,019 
(683)
1,910 
Changes in assets and liabilities:
 
 
 
Prepaid expenses and other assets
(662)
(317)
(911)
Accounts payable
875 
(193)
2,099 
Due to former parent
 
 
(207)
Accrued expenses and other current liabilities
(165)
1,747 
3,308 
Net cash used in operating activities
(15,795)
(10,499)
(74,573)
Cash flows from investing activities:
 
 
 
Change in restricted cash
 
 
(101)
Net cash received in acquisition
 
168 
168 
Purchase of short-term investments
 
 
(37,532)
Maturities of short-term investments
 
 
37,497 
Cash paid for purchase of equipment and furnishings
 
(53)
(739)
Disposal of equipment and furnishings
 
 
(1)
Cash paid for lease deposit
 
 
(45)
Net cash transferred in spin-off transaction
(87)
 
(87)
Net cash (used in) provided by investing activities
(87)
115 
(840)
Cash flows from financing activities:
 
 
 
Net proceeds from issuance of common stock
13,937 
18,609 
78,919 
Cash paid for repurchase of common stock warrants
(266)
 
(266)
Cash paid for repurchase of common stock
 
 
(3,849)
Net proceeds from exercise of common stock options
 
150 
610 
Net proceeds from exercise of common stock warrants
5,672 
 
5,822 
Common stock issued in connection with ESPP
39 
 
54 
Net proceeds from issuance of convertible notes payable
500 
500 
1,000 
Repayments of capital lease obligations
(10)
(73)
(220)
Cash advances from former parent company, net
 
 
8,766 
Net cash provided by financing activities
19,872 
19,186 
90,836 
Net increase in cash and cash equivalents
3,990 
8,802 
15,423 
Cash and cash equivalents at the beginning of period
11,433 
6,891 
 
Cash and cash equivalents at end of period
15,423 
15,693 
15,423 
Supplemental disclosure of cash flow information:
 
 
 
Cash received during the period for interest
 
727 
Cash paid during the period for interest
 
 
12 
Supplemental disclosure of non-cash investing and financing activities:
 
 
 
Settlement of corporate formation expenses in exchange for common stock
 
 
978 
Fair value of warrants issued in connection with common stock recorded as a cost of equity
 
13,232 
18,038 
Issuance of common stock in exchange for outstanding warrants
 
 
3,120 
Fair value of shares mandatorily redeemable for cash upon the exercise of warrants
 
 
785 
Net liabilities distributed in spin-off transaction, net of cash transferred
2,246 
 
2,246 
Issuance of common stock in payment of contingent purchase price consideration milestone
1,579 
 
1,579 
Reclassification of warrant liability upon exercise
10,741 
102 
10,741 
Allocation of management expenses
 
 
551 
Fair value of stock options modified
 
674 
674 
Equipment and furnishings exchanged for common stock
 
 
48 
Equipment and furnishings acquired through capital lease
 
80 
277 
Value of restricted stock units and common stock issued in lieu of bonuses included in accrued expenses
 
427 
634 
Non-cash lease deposit
 
 
50 
NeuVax™ (Apthera, Inc.) Acquisition:
 
 
 
Fair value of shares issued at closing
 
6,367 
6,367 
Fair value of contingent purchase price consideration
6,460 
6,460 
6,460 
Net assets acquired, excluding cash of $168
$ 12,827 
$ 12,827 
$ 12,827 
Condensed Consolidated Statements of Cash Flows (Parenthetical) (USD $)
In Thousands, unless otherwise specified
9 Months Ended 117 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Cash excluding from net assets acquired
$ 168 
$ 168 
$ 168 
Description of Business and Basis of Presentation
Description of Business and Basis of Presentation

1. Description of Business and Basis of Presentation

Galena Biopharma, Inc. (“we,” “us,” “our,” “Galena” or the “Company”) is a biopharmaceutical company focused on developing innovative, next-generation cancer immunotherapies which address major unmet medical needs to advance care. Galena is developing innovative, peptide antigen-based “off the shelf” cancer immunotherapies for potential application to treatment of large populations of Cancer Survivors. Peptide vaccines have several potential clinical advantages over existing cancer treatments including excellent safety profiles, long-lasting protection through immune system activation, as well as an acceptable mode of administration (intradermal injection). In addition, there are potential commercial advantages in that these are readily and reproducibly manufactured products that could have a very wide reach into the physicians’ office, with no special requirements for delivery to the office or to patients.

A key differentiator in Galena’s approach is a focus on “minimal residual disease” that may remain in Cancer Survivors. The strategy is to prevent recurrence in early stage patient groups who may harbor “occult” residual cancer cells that are not detectable by current imaging and biomarkers, and despite adjuvant therapy and radiation therapy will relapse in significant numbers over time.

Our lead product candidate, NeuVax™ (nelipepimut-S) is the immmunodominant nonapeptide derived from the extracellular domain of the HER2 protein, a well-established target for therapeutic intervention in breast cancer. The nelipepimut sequence stimulates specific CD8+ cytotoxic T lymphocytes (CTL) following binding to HLA-A2/A3 molecules on antigen presenting cells (APC). These activated specific CTLs recognize, neutralize and destroy through cell lysis HER2 expressing cancer cells, including occult cancer cells and micrometastatic foci. The nelipepimut immune response can also generate CTLs to other immunogenic peptides through inter- and intra-antigenic epitope spreading. Based on a successful Phase 2 trial, which achieved its primary endpoint of disease free survival (DFS), the Food and Drug Administration (FDA) granted NeuVax™ a Special Protocol Assessment (SPA) for its Phase 3 PRESENT (Prevention of Recurrence in Early-Stage, Node-Positive Breast Cancer with Low to Intermediate HER2 Expression with NeuVax Treatment) trial. The Phase 3 PRESENT trial is ongoing and additional information on the study can be found at www.neuvax.com. If the randomized, double-blinded, multinational, 700 patient PRESENT trial is successful, the Company intends to seek U.S. FDA commercial registration of NeuVax™.

Based on a pilot Phase 2a study and preclinical evidence suggesting enhanced efficacy of using NeuVax™ in combination with Herceptin ® (trastuzumab: Genentech/Roche), NeuVax™ is also being developed in combination with Herceptin in a randomized Phase 2 clinical trial.

Our second product candidate, Folate Binding Protein (FBP), a targeted vaccine which consists of the E39 peptide over-expressed (20-80 fold) in more than 90% of ovarian and endometrial cancers, is currently in a Phase 1/2 clinical trial.

The Company was incorporated as Argonaut Pharmaceuticals, Inc., in Delaware, on April 3, 2006. The Company changed its name to RXi Pharmaceuticals Corporation on November 28, 2006.

We acquired our NeuVax™ product candidate in April 2011. Prior to that time, we were engaged primarily in conducting discovery research and preclinical development activities based on RNAi. In connection with our acquisition of NeuVax™, we reduced the scope of our RNAi activities.

On September 26, 2011, the Company changed its name to Galena Biopharma, Inc. from RXi Pharmaceuticals Corporation in connection with the Company’s separation into two companies: (i) Galena, a late-stage oncology drug development company; and (ii) RXi, which continues to develop novel RNAi-based therapies utilizing our historical RNAi assets. RXi was initially incorporated as RNCS, Inc. and assumed the name RXi Pharmaceuticals Corporation in conjunction with the change in the Company’s name to Galena. On April 27, 2012, Galena completed the partial spin-off of RXi. (See Note 4)

The Company has not generated any revenue from inception through September 30, 2012 and is considered a development-stage company for accounting purposes. The Company may not generate product revenue in the foreseeable future, if ever. The Company expects to incur significant operating losses as it advances its product candidates through the drug development and regulatory process. The Company expects to continue to devote a substantial portion of its resources to research and development programs. As a result of the costs expected to be incurred in connection with our recently commenced clinical trials of NeuVax™ and FBP, the Company expects that our research and development expense will increase significantly from historic levels for the foreseeable future. The Company will need to generate significant revenue to achieve profitability and might never do so. In the absence of product revenue, our potential sources of operational funding are expected to be the proceeds from equity financings, funded research and development payments and payments received under partnership and collaborative agreements. There is no guarantee that additional funding will be available to the Company on acceptable terms, or at all. If the Company fails to obtain additional funding when needed, it would be forced to scale back or terminate operations or to seek to merge with or to be acquired by another company.

 

Use of Estimates

The preparation of consolidated financial statements in accordance with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of expenses during the reporting period. Actual results could differ from these estimates.

Derivative Financial Instruments

The Company does not enter into any derivative contracts for speculative purposes. From time to time, the Company issues warrants or options to purchase our common stock to vendors as consideration to perform services. The Company may also issue warrants as part of financing transactions. The Company recognizes all derivatives, including warrants, as assets or liabilities measured at fair value, with changes in fair value of derivatives reflected as current period income or loss unless the derivatives qualify for hedge accounting and are accounted for as such. In accordance with Financial Accounting Standards Board (“FASB”) Accounting Standards Codification (“ASC”) Topic 815-40, “ Derivatives and Hedging — Contracts in Entity’s Own Stock ” the value of some of our warrants is required to be recorded as a liability, since the holders have an option to put the warrants back to the Company in specified events (see Note 10).

Principles of Consolidation

The consolidated financial statements include the accounts of Galena and its consolidated subsidiary. All material intercompany accounts have been eliminated in consolidation.

Other Income (Expense)

Other income (expense) consists of the following (in thousands):

 

     For the Three
Months Ended
September 30,
2012
    For the Three
Months Ended
September 30,
2011
    For the Nine
Months Ended
September 30,
2012
    For the Nine
Months Ended
September 30,
2011
 

Change in the fair value of warrants potentially settleable in cash

   $ (262   $ (1,052   $ (11,899   $ 1,042   

Change in the fair value of contingent purchase price consideration

     (471     655       (2,019     683   

Miscellaneous other expense

     —          —          —          (2
  

 

 

   

 

 

   

 

 

   

 

 

 

Total other income (expense)

   $ (733   $ (397   $ (13,918   $ 1,723   
  

 

 

   

 

 

   

 

 

   

 

 

 

Comprehensive Loss

The Company’s comprehensive loss is equal to its net loss for all periods presented.

Recent Accounting Pronouncements
Recent Accounting Pronouncements

2. Recent Accounting Pronouncements

In July 2012, the FASB issued ASU No. 2012-02, Intangibles — Goodwill and Other (Topic 350): Testing Indefinite-Lived Intangible Assets, a new accounting pronouncement intended to simplify how entities test indefinite-lived intangible assets other than goodwill for impairment. The new standard permits an entity to first assess qualitative factors to determine whether it is “more likely than not” (defined as having a likelihood of more than 50%) that an indefinite-lived intangible asset is impaired, in order to determine whether further impairment testing is necessary. The new standard is effective for annual and interim impairment tests performed for fiscal years beginning after September 15, 2012, and early adoption is permitted. The new standard is not expected to have a material impact on the Company’s consolidated financial statements.

NeuVaxTM Acquisition
NeuVaxTM Acquisition

3. NeuVax™ Acquisition

On April 13, 2011, in concert with the decision by the Company’s Board of Directors to diversify its development programs and to become a late stage clinical development company, the Company acquired its late stage product candidate NeuVax™ through a merger acquisition of Apthera, Inc., a Delaware corporation (“Apthera”), with Apthera surviving as a wholly-owned subsidiary of the Company. At the closing of the merger, the Company issued to Apthera’s stockholders approximately 5.0 million shares of common stock of the Company and agreed to pay to the former Apthera shareholders future contingent consideration of up to $32 million based on the achievement of specified development and commercial milestones relating to the Company’s NeuVax™ product candidate. The contingent consideration is payable, at the election of the Company, in cash or in additional shares of common stock.

The goodwill associated with the acquisition is not deductible for tax purposes.

 

The purchase price consideration and allocation of purchase price were as follows:

 

     (in 000’s)  

Calculation of allocable purchase price:

  

Fair value of shares issued at closing including escrowed shares expected to be released

   $ 6,367 (i)

Estimated value of contingent consideration

     6,460   
  

 

 

 

Total allocable purchase price

   $ 12,827   
  

 

 

 

Allocation of purchase price:

  

Cash

   $ 168   

Prepaid expenses and other current assets

     14   

Equipment and furnishings

     11   

Goodwill

     5,898   

In-process research and development

     12,864   

Accounts payable

     (931 )

Accrued expenses and other current liabilities

     (143 )

Notes payable

     (1 )

Deferred tax liability, non-current

     (5,053 )
  

 

 

 
   $ 12,827   
  

 

 

 

 

(i) The value of the Company’s common stock was based upon a per share value of $1.28, the closing price of the Company’s common stock as reported on The NASDAQ Capital Market on April 13, 2011.

The Company recorded the estimated fair value of the contingent consideration at $6.5 million based on the expected probability of achieving the specified development and commercial milestones relating to the Company’s NeuVax™ product candidate and then applying a discount rate, based on a corporate debt interest rate index publicly issued, to the expected future payments. The expected timing and probability of achieving each milestone and the discount rates applied are reviewed quarterly using the most current information to measure the contingent considertation as of the reporting date. On January 19, 2012, the first milestone was achieved, and the Company issued into escrow in favor of the former Apthera shareholders $1,000,000, or 1,315,849 shares, of common stock in payment of the related contingent consideration. The number of shares was based on the $0.76 closing price of the Company’s common stock as reported on The NASDAQ Capital Market on January 18, 2012, the day prior to achievement of the first milestone. In September 2012, the escrowed shares were released to the former Apthera shareholders from escrow, and the Company paid to the former Apthera shareholders cash of $35,016, representing an interest factor of ten percent (10%) per annum on the $1,000,000 amount of the milestone payment from February 10, 2012 through the day immediately prior to the release of the escrowed shares. During the nine months ended September 30, 2012, the Company recorded additional other expense of $579,000 related to the change in the fair value of the escrowed shares up to the date of release from escrow.

The increase in the fair value of the contingent liability during the nine months ended September 30, 2012 was $2,019,000, which is included in other income (expense) in the accompanying condensed consolidated statements of expenses. The fair value of the contingent liability at September 30, 2012 was $6,791,000. Of this amount, $925,000 is recorded as a current contingent liability.

The following presents the pro forma net loss and pro forma net loss per common share for the three and nine months ended September 30, 2011 (amounts in thousands, except per share data):

 

     For the Three
Months Ended
September 30, 2011
    For the Nine
Months Ended
September 30, 2011
 

Net loss from continuing operations

   $ (4,194 )   $ (8,533 )

Net loss from discontinued operations

   $ (1,641 )   $ (5,898 )

Net loss per common share, continuing operations

   $ (0.10 )   $ (0.24

Net loss per common share, discontinued operations

   $ (0.04 )   $ (0.17

Net loss per common share

   $ (0.14 )   $ (0.41 )
RXi Spin-Off
RXi Spin-Off

4. RXi Spin-Off

Contribution Agreement

On September 24, 2011, the Company entered into a contribution agreement with RXi pursuant to which we assigned and contributed to RXi substantially all of the Company’s RNAi-related technologies and assets. The contributed assets consist primarily of our novel RNAi compounds and licenses relating to our RNAi technologies, as well as the lease of our Worcester, Massachusetts laboratory facility, fixed assets and other equipment located at the facility and our employment arrangements with certain scientific, corporate and administrative personnel who became employees of RXi. The Company also contributed $1.5 million of cash to the capital of RXi.

Pursuant to the contribution agreement, RXi assumed certain accrued expenses of our RXI-109 development program and all subsequent obligations under the contributed licenses, employment arrangements and other agreements. RXi also has agreed to make future milestone payments to us of up to $45 million, consisting of two one-time payments of $15 million and $30 million, respectively, if RXi achieves annual net sales equal to or greater than $500 million and $1 billion, respectively, of any covered products that may be developed with the contributed RNAi technologies.

In the contribution agreement, the Company made customary representations and warranties to RXi regarding the contributed assets and other matters, and agreed to indemnify RXi against losses arising from a breach of its representations, warranties and covenants set forth in the contribution agreement.

Securities Purchase Agreement

On September 24, 2011, the Company also entered into a securities purchase agreement with RXi and two institutional investors, pursuant to which the investors agreed to purchase a total of $9,500,000 of Series A Preferred Stock of RXi (“RXi Preferred Stock”) at the closing of the spin-off of RXi, and to lend up to $1,500,000 to RXi to fund its operations between signing and closing (the “Bridge Loan”). The outstanding principal and accrued interest from the Bridge Loan was converted into RXi Preferred Stock at the closing of the spin-off of RXi and represents a portion of the $9,500,000 total investment in RXi Preferred Stock.

The RXi Preferred Stock will be convertible by a holder at any time into shares of RXi common stock, except to the extent that the holder would own more than 9.999% of the shares of RXi common stock outstanding immediately after giving effect to such conversion. Without regard to this conversion limitation, the shares of the RXi Preferred Stock to be held by the Investors upon completion of the RXi financing and the spin-off of RXi will be convertible into shares of RXi common stock representing approximately 83% of the shares of RXi common stock that would be outstanding, assuming the conversion in full of the RXi Preferred Stock, which we refer to as the “as-converted common stock.”

Spin-Off

The Company agreed in the securities purchase agreement to distribute to our stockholders on a share-for-share basis approximately 8% of the as-converted common stock of RXi, which distribution was completed on April 27, 2012. The Company distributed a total of 66,959,894 RXi shares to its shareholders on April 27, 2012. The Company retained 32,734,235 shares of common stock of RXi, which are subject to a one-year lock up period. For accounting purposes, RXi’s historical carrying amounts at the date of the spin-off are used as the basis for recording the Company’s retained ownership in RXi. Since RXi’s liabilities exceeded its assets at the spin-off date, Galena’s investment in RXi is carried at zero. The value of RXi shares held by the Company at September 30, 2012 was $0.11 per share or approximately $3,600,000, based on the average of high and low bid prices of RXi shares as reported in the OTC Bulletin Board.

The Company classified the RXi activities, including for previously reported periods, as discontinued operations in the accompanying condensed consolidated statements of expenses. The net assets of RXi were removed from the condensed consolidated balance sheet as of the date of the spin-off, and were recorded as an equity distribution. Summarized balance sheet information related to the net assets distributed in the spin-off are as follows (in thousands):

 

     April 27,
2012
    December 31,
2011
 

Assets

    

Cash and cash equivalents

   $ 87      $ 556   

Other current assets

     66        783   

Equipment and furnishings

     315        355   

Liabilities

    

Accounts payable and accrued liabilities

     (1,607 )     (1,747 )

Convertible notes

     (1,000 )     (500 )

Capital lease obligations

     (20 )     (34 )
  

 

 

   

 

 

 

Net liabilities

   $ (2,159 )   $ (587 )
  

 

 

   

 

 

 

Purchase Agreement Terms and Conditions

In the securities purchase agreement, the parties made customary representations and warranties to the other parties and agreed to indemnify each other against losses arising from a breach of their respective representations, warranties and covenants. In accordance with the securities purchase agreement, on April 27, 2012, RXi reimbursed the Company and the Investors $300,000 and $100,000, respectively, for transaction costs relating to the contribution agreement, the securities purchase agreement and the transactions called for by the agreements.

 

RXi Convertible Promissory Notes

Pursuant to the securities purchase agreement, the RXi investors purchased $1,000,000 of secured convertible promissory notes of RXi, the proceeds of which were used to fund RXi’s operations pending the spin-off of RXi. The RXi convertible notes bore interest at a rate of 7% per annum and were converted into shares of RXi Preferred Stock at a conversion price of $1,000 per share in conjunction with the completion of the spin-off.

Fair Value Measurements
Fair Value Measurements

5. Fair Value Measurements

The Company follows the provisions of FASB ASC Topic 820, “Fair Value Measurements and Disclosures” (“ASC 820”) for the Company’s financial assets and liabilities that are re-measured and reported at fair value at each reporting period, and are re-measured and reported at fair value at least annually using a fair value hierarchy that is broken down into three levels. Level inputs are as defined as follows:

Level 1 — quoted prices in active markets for identical assets or liabilities.

Level 2 — other significant observable inputs for the assets or liabilities through corroboration with market data at the measurement date.

Level 3 — significant unobservable inputs that reflect management’s best estimate of what market participants would use to price the assets or liabilities at the measurement date.

The Company categorized its cash equivalents as a Level 1 hierarchy. The valuation for Level 1 was determined based on a “market approach” using quoted prices in active markets for identical assets. Valuations of these assets do not require a significant degree of judgment. The Company categorized its warrants potentially settled in cash as a Level 2 hierarchy. The warrants are measured at fair market value on a recurring basis and are marked to market each quarter-end until they are settled. The contingent purchase price consideration is categorized as a Level 3 hierarchy and is measured at its estimated fair value on a recurring basis and is adjusted at each quarter-end until it is completely settled. The contingent price consideration is valued based on the expected timing of milestones, the expected probability of success for each milestone and the updated discount rates based on a corporate debt interest rate index publicly issued.

 

The following table presents information about our assets and liabilities that are measured at fair value on a recurring basis as of September 30, 2012 and December 31, 2011, respectively, and indicates the fair value hierarchy of the valuation techniques we utilized to determine such fair value (in thousands):

 

Description    September 30,
2012
     Quoted
Prices in
Active
Markets
(Level 1)
     Significant
Other
Observable
Inputs
(Level 2)
     Unobservable
Inputs
(Level 3)
 

Assets:

           

Cash equivalents

   $ 14,746       $ 14,746       $ —         $ —     
  

 

 

    

 

 

    

 

 

    

 

 

 

Total assets

   $ 14,746       $ 14,746       $ —         $ —     
  

 

 

    

 

 

    

 

 

    

 

 

 

Liabilities:

           

Warrants potentially settleable in cash

   $ 4,904       $ —         $ 4,904       $ —     

Contingent purchase price consideration

     6,791         —           —           6,791   
  

 

 

    

 

 

    

 

 

    

 

 

 

Total liabilities

   $ 11,695       $ —         $ 4,904       $ 6,791   
  

 

 

    

 

 

    

 

 

    

 

 

 
Description    December 31,
2011
     Quoted
Prices in
Active
Markets
(Level 1)
     Significant
Other
Observable
Inputs
(Level 2)
     Unobservable
Inputs
(Level 3)
 

Assets:

           

Cash equivalents

   $ 11,433       $ 11,433       $ —         $ —     
  

 

 

    

 

 

    

 

 

    

 

 

 

Total assets

   $ 11,433       $ 11,433       $ —         $ —     
  

 

 

    

 

 

    

 

 

    

 

 

 

Liabilities:

           

Warrants potentially settleable in cash

   $ 3,746       $ —         $ 3,746       $ —     

Contingent purchase price consideration

     6,351         —           —           6,351   
  

 

 

    

 

 

    

 

 

    

 

 

 

Total liabilities

   $ 10,097       $ —         $ 3,746       $ 6,351   
  

 

 

    

 

 

    

 

 

    

 

 

 

A reconciliation of the beginning and ending Level 3 liabilities for the nine months ended September 30, 2012 is as follows (in thousands):

 

    3 Months
Ended
September 30,
2012
     9 Months
Ended
September 30,
2012
 

Balance, beginning of period

  $ 6,320       $ 6,351   

Payment of contingent purchase price consideration milestone

    —           (1,579

Changes in the estimated fair value of contingent acquisition purchase price consideration

    471         2,019   
 

 

 

    

 

 

 

Balance at September 30, 2012

  $ 6,791       $ 6,791   
 

 

 

    

 

 

 

Fair Value of Financial Instruments

The carrying amounts reported in the balance sheet for cash, accounts payable, capital leases and convertible notes payable approximate their fair values due to their short-term nature and market rates of interest.

Stock Based Compensation
Stock Based Compensation

6. Stock-Based Compensation

The Company follows the provisions of the FASB ASC Topic 718, “ Compensation — Stock Compensation ” (“ASC 718”), which requires the measurement and recognition of compensation expense for all stock-based payments and awards, including stock options and warrants made to employees, non-employee directors, and consultants. In accordance with the provisions of ASC 718, stock-based compensation expense based on the grant date fair value of the underlying stock is recognized as an expense over the requisite service period.

Stock-based compensation for services rendered by non-employees is recognized as compensation expense in accordance with the requirements of FASB ASC Topic 505-50, “ Equity Based Payments to Non-Employees.”

Non-employee option grants that do not vest immediately upon grant are recorded as an expense over the vesting period of the underlying stock options. At the end of each financial reporting period prior to vesting, the value of these options, as calculated using the Black-Scholes option-pricing model, will be re-measured using the fair value of the Company’s common stock and the non-cash compensation recognized during the period will be adjusted accordingly. Since the fair market value of options granted to non-employees is subject to change in the future, the amount of the future compensation expense will include fair value re-measurements until the stock options are fully vested.

The Company is currently using the Black-Scholes option-pricing model to determine the fair value of all its option grants. For option grants in the three and nine months ended September 30, 2012 and 2011, the following assumptions were used:

 

     For the Three Months Ended September 30,     For the Nine Months Ended September 30,  
     2012     2011     2012     2011  

Weighted average risk-free interest rate

     0.85 %     1.03 %     1.06 %     1.59 %

Weighted average expected volatility

     75.35     98.94 %     75.67     103.27

Weighted average expected lives (years)

     6.25        5.34        6.13        5.49   

Weighted average expected dividend yield

     0.00 %     0.00 %     0.00 %     0.00 %

The weighted average fair values of options granted during the nine-month period ended September 30, 2012 and 2011 were $0.59 and $0.91 per share, respectively.

The weighted average fair values of options granted during the three-month period ended September 30, 2012 and 2011 were $1.23 and $0.66 per share, respectively.

The Company’s expected volatility is based on a combination of implied volatilities of similar publicly traded entities. The expected life assumptions for employee grants were based upon the simplified method provided for under ASC 718-10. The expected life assumptions for non-employees were based upon the contractual term of the option. The dividend yield assumption of zero is based upon the fact that the Company has never paid cash dividends and presently has no intention of paying cash dividends. The risk-free interest rate used for each grant was also based upon prevailing short-term interest rates. The Company has estimated an annualized forfeiture rate of 15.0% for options granted to its employees, 8.0% for options granted to senior management and no forfeiture rate for the directors. The Company will record additional expense if the actual forfeitures are lower than estimated and will record a recovery of prior expense if the actual forfeiture rates are higher than estimated.

The following table summarizes stock option activity from January 1, 2012 through September 30, 2012:

 

     Total
Number of
Shares
    Weighted
Average
Exercise
Price
     Aggregate
Intrinsic
Value
 

Outstanding at January 1, 2012

     6,163,137      $ 3.03       $ —     

Granted

     1,650,000        0.92         —     

Exercised

     (11,250     0.76         10,463   

Cancelled

     (261,816     3.51         —     
  

 

 

      

Outstanding at September 30, 2012

     7,540,071      $ 2.55       $ 3,386,718   
  

 

 

      

Options exercisable at September 30, 2012

     5,535,205      $ 3.08       $ 1,928,425   
  

 

 

      

The aggregate intrinsic values of outstanding and exercisable options at September 30, 2012 were calculated based on the closing price of the Company’s common stock as reported on The NASDAQ Capital Market on September 28, 2012 of $1.78 per share less the exercise price of the options. The aggregate intrinsic values of options exercised was calculated based on the difference between the exercise price of the options and the market price of the Company’s common stock on the date of exercise.

Net Loss Per Share
Net Loss Per Share

7. Net Loss Per Share

The Company accounts for and discloses net loss per common share in accordance with FASB ASC Topic 260 “ Earnings per Share.” Basic net loss per common share is computed by dividing net loss attributable to common stockholders by the weighted average number of common shares outstanding. Diluted net loss per common share is computed by dividing net loss attributable to common stockholders by the weighted average number of common shares that would have been outstanding during the period assuming the issuance of common shares for all potential dilutive common shares outstanding. Potential common shares consist of shares issuable upon the exercise of stock options and warrants. Because the inclusion of potential common shares would be anti-dilutive for all periods presented diluted net loss per common share is the same as basic net loss per common share.

For the three and nine months ended September 30, 2012, 7,540,000 shares of common stock issuable upon the exercise of stock options were excluded from the computation of diluted earnings per share because the effect would be antidilutive. For the three months ended September 30, 2012, 5,747,000 shares of common stock issuable upon the exercise of warrants were excluded from the computation of diluted earnings per share for the same reason.

For the three and nine months ended September 30, 2011, 6,452,000 shares of common stock issuable upon the exercise of stock options were excluded from the computation of diluted earnings per share because the effect would be antidilutive. For the three and nine months ended September 30, 2011, 20,051,000 shares of common stock issuable upon the exercise of warrants were excluded from the computation of dilutive earnings per share for the same reason.

License Agreements
License Agreements

8. License Agreements

As part of its business, the Company enters into licensing agreements that often require milestone and royalty payments based on the progress of the asset through development stages. Milestone payments may be required, for example, upon approval of the product for marketing by a regulatory agency. In certain agreements, the Company is required to make royalty payments based upon a percentage of product sales.

Individual milestone payments may be material, and multiple milestones may be reached in the same period. The aggregate payments associated with the milestones could adversely affect the results of operations or affect the comparability of our period-to-period results. In addition, these license arrangements often give the Company the discretion to unilaterally terminate development of the product candidate and avoid making the contingent payments; however, the Company is unlikely to cease development if the product candidate achieves clinical testing objectives. The Company’s contractual obligations relating to minimum annual maintenance fees and milestone payments have not changed significantly from December 31, 2011.

Stockholders' Equity
Stockholders' Equity

9. Stockholders’ Equity

On April 13, 2012, the Company completed an underwritten public offering of 9,751,000 shares of common stock for gross proceeds of $14,626,500, resulting in approximately $13,937,000 of net proceeds to the Company after deducting the underwriting discounts and commissions and offering expenses.

Warrants
Warrants

10. Warrants

The following is a summary of warrant activity for the nine months ended September 30, 2012 (in thousands):

 

     April
2011
Warrants
    March
2011
Warrants
    March
2010
Warrants
    August
2009
Warrants
     Consultant
Warrants
     Total  

Warrants outstanding, January 1, 2012

     9,470        2,400        540        978         733         14,121   

Warrants issued

     —          —          —          —           400         400   

Warrants exercised

     (6,595     (1,999     (180     —           —           (8,774
  

 

 

   

 

 

   

 

 

   

 

 

    

 

 

    

 

 

 

Warrants outstanding, September 30, 2012

     2,875        401        360        978         1,133         5,747   
  

 

 

   

 

 

   

 

 

   

 

 

    

 

 

    

 

 

 

Expiration

    
 
April
2017
  
  
   
 
March
2016
  
  
   
 
March
2016
  
  
   
 
August
2014
  
  
    
 
January
2014
  
  
  

Warrants consist of liability-classified warrants and equity-classified warrants.

Warrants classified as liabilities

Liability-classified warrants consist of warrants issued in connection with equity financings in April 2011, March 2011, March 2010, and March 2009. These warrants were determined not to be indexed to the Company’s own stock as they are potentially settleable in cash.

The estimated fair value of outstanding warrants accounted for as liabilities is determined at each balance sheet date. The change in the estimated fair value of the warrant liability is recorded in the condensed consolidated statement of expenses as other income (expense). The fair value of the warrants is estimated using the Black-Scholes option pricing model with the following inputs:

 

     As of September 30, 2012  
     April 2011
Warrants
    March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
 

Strike price

   $ 0.65      $ 0.65      $ 2.50      $ 4.50   

Expected term

     4.56        3.43        3.50        1.80   

Volatility

     78.93     67.96     68.18     62.59

Risk free rate

     0.55     0.38     0.39     0.22
     As of December 31, 2011  
     April 2011
Warrants
    March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
 

Strike price

   $ 0.65      $ 0.65      $ 2.50      $ 4.50   

Expected term

     5.30        0.03        4.80        2.60   

Volatility

     98.91     98.91     98.91     98.91

Risk free rate

     0.83     0.02     0.83     0.31

The Company’s expected volatility is based on a combination of implied volatilities of similar publicly traded entities. The expected life assumption is based on the remaining contractual terms of the warrants. The risk-free rate is based on the zero coupon rates in effect at the time of issuance. The dividend yield used in the pricing model is zero, because the Company has no present intention to pay cash dividends.

The change in fair value of the warrant liability during the three months ended September 30, 2012 was as follows (in thousands):

 

     April 2011
Warrants
    March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
    Total  

Warrant liability, June 30, 2012

   $ 3,736      $ 1,013      $ 305      $ 175      $ 5,229   

Fair value of warrants exercised

     (25     (562     —          —          (587

Change in fair value of warrants

     286        54        (55     (23     262   
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Warrant liability, September 30, 2012

   $ 3,997      $ 505      $ 250      $ 152      $ 4,904   
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

The change in fair value of the warrant liability during the nine months ended September 30, 2012 was as follows (in thousands):

 

     April 2011
Warrants
    March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
     Total  

Warrant liability, January 1, 2012

   $ 3,154      $ 412      $ 116      $ 64       $ 3,746   

Fair value of warrants exercised

     (8,086     (2,401     (254     —           (10,741

Change in fair value of warrants

     8,929        2,494        388        88         11,899   
  

 

 

   

 

 

   

 

 

   

 

 

    

 

 

 

Warrant liability, September 30, 2012

   $ 3,997      $ 505      $ 250      $ 152       $ 4,904   
  

 

 

   

 

 

   

 

 

   

 

 

    

 

 

 

The change in fair value of the warrant liability during the three months ended September 30, 2011 was as follows (in thousands):

 

     April 2011
Warrants
    March 2011
Warrants
     March 2010
Warrants
     August 2009
Warrants
    Total  

Warrant liability, June 30, 2011

   $ 12,320      $ 1,310       $ 324       $ 300      $ 14,254   

Fair value of warrants exercised

     (80     —           —           —          (80

Change in fair value of warrants

     903        162         —           (13     1,052   
  

 

 

   

 

 

    

 

 

    

 

 

   

 

 

 

Warrant liability, September 30, 2011

   $ 13,143      $ 1,472       $ 324       $ 287      $ 15,226   
  

 

 

   

 

 

    

 

 

    

 

 

   

 

 

 

 

The change in fair value of the warrant liability during the nine months ended September 30, 2011 was as follows (in thousands):

 

     April 2011
Warrants
     March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
    Total  

Warrant liability, January 1, 2011

   $ —         $ —        $ 1,195      $ 1,943      $ 3,138   

Fair value of warrants issued

     11,438         1,794        —          —          13,232   

Fair value of warrants exercised

     —           (102     —          —          (102

Change in fair value of warrants

     1,705         (220     (871     (1,656     (1,042
  

 

 

    

 

 

   

 

 

   

 

 

   

 

 

 

Warrant liability, September 30, 2011

   $ 13,143       $ 1,472      $ 324      $ 287      $ 15,226   
  

 

 

    

 

 

   

 

 

   

 

 

   

 

 

 

Warrants classified as equity

Equity-classified warrants consist of warrants issued in connection with consulting services. These warrants are recorded in equity at fair value upon issuance, and are not reported as liabilities on the balance sheet.

Subsequent Events
Subsequent Events

11. Subsequent Events

The Company evaluated all events or transactions that occurred after September 30, 2012 up through the date these financial statements were issued. The Company did not have any material recognizable or unrecognizable subsequent events.

Description of Business and Basis of Presentation (Policies)

Use of Estimates

The preparation of consolidated financial statements in accordance with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of expenses during the reporting period. Actual results could differ from these estimates.

Derivative Financial Instruments

The Company does not enter into any derivative contracts for speculative purposes. From time to time, the Company issues warrants or options to purchase our common stock to vendors as consideration to perform services. The Company may also issue warrants as part of financing transactions. The Company recognizes all derivatives, including warrants, as assets or liabilities measured at fair value, with changes in fair value of derivatives reflected as current period income or loss unless the derivatives qualify for hedge accounting and are accounted for as such. In accordance with Financial Accounting Standards Board (“FASB”) Accounting Standards Codification (“ASC”) Topic 815-40, “ Derivatives and Hedging — Contracts in Entity’s Own Stock ” the value of some of our warrants is required to be recorded as a liability, since the holders have an option to put the warrants back to the Company in specified events (see Note 10).

Principles of Consolidation

The consolidated financial statements include the accounts of Galena and its consolidated subsidiary. All material intercompany accounts have been eliminated in consolidation.

In July 2012, the FASB issued ASU No. 2012-02, Intangibles — Goodwill and Other (Topic 350): Testing Indefinite-Lived Intangible Assets, a new accounting pronouncement intended to simplify how entities test indefinite-lived intangible assets other than goodwill for impairment. The new standard permits an entity to first assess qualitative factors to determine whether it is “more likely than not” (defined as having a likelihood of more than 50%) that an indefinite-lived intangible asset is impaired, in order to determine whether further impairment testing is necessary. The new standard is effective for annual and interim impairment tests performed for fiscal years beginning after September 15, 2012, and early adoption is permitted. The new standard is not expected to have a material impact on the Company’s consolidated financial statements.

The Company follows the provisions of FASB ASC Topic 820, “Fair Value Measurements and Disclosures” (“ASC 820”) for the Company’s financial assets and liabilities that are re-measured and reported at fair value at each reporting period, and are re-measured and reported at fair value at least annually using a fair value hierarchy that is broken down into three levels. Level inputs are as defined as follows:

Level 1 — quoted prices in active markets for identical assets or liabilities.

Level 2 — other significant observable inputs for the assets or liabilities through corroboration with market data at the measurement date.

Level 3 — significant unobservable inputs that reflect management’s best estimate of what market participants would use to price the assets or liabilities at the measurement date.

The Company categorized its cash equivalents as a Level 1 hierarchy. The valuation for Level 1 was determined based on a “market approach” using quoted prices in active markets for identical assets. Valuations of these assets do not require a significant degree of judgment. The Company categorized its warrants potentially settled in cash as a Level 2 hierarchy. The warrants are measured at fair market value on a recurring basis and are marked to market each quarter-end until they are settled. The contingent purchase price consideration is categorized as a Level 3 hierarchy and is measured at its estimated fair value on a recurring basis and is adjusted at each quarter-end until it is completely settled. The contingent price consideration is valued based on the expected timing of milestones, the expected probability of success for each milestone and the updated discount rates based on a corporate debt interest rate index publicly issued.

The Company follows the provisions of the FASB ASC Topic 718, “ Compensation — Stock Compensation ” (“ASC 718”), which requires the measurement and recognition of compensation expense for all stock-based payments and awards, including stock options and warrants made to employees, non-employee directors, and consultants. In accordance with the provisions of ASC 718, stock-based compensation expense based on the grant date fair value of the underlying stock is recognized as an expense over the requisite service period.

The Company’s expected volatility is based on a combination of implied volatilities of similar publicly traded entities. The expected life assumptions for employee grants were based upon the simplified method provided for under ASC 718-10. The expected life assumptions for non-employees were based upon the contractual term of the option. The dividend yield assumption of zero is based upon the fact that the Company has never paid cash dividends and presently has no intention of paying cash dividends. The risk-free interest rate used for each grant was also based upon prevailing short-term interest rates. The Company has estimated an annualized forfeiture rate of 15.0% for options granted to its employees, 8.0% for options granted to senior management and no forfeiture rate for the directors. The Company will record additional expense if the actual forfeitures are lower than estimated and will record a recovery of prior expense if the actual forfeiture rates are higher than estimated.

Stock-based compensation for services rendered by non-employees is recognized as compensation expense in accordance with the requirements of FASB ASC Topic 505-50, “ Equity Based Payments to Non-Employees.”

Non-employee option grants that do not vest immediately upon grant are recorded as an expense over the vesting period of the underlying stock options. At the end of each financial reporting period prior to vesting, the value of these options, as calculated using the Black-Scholes option-pricing model, will be re-measured using the fair value of the Company’s common stock and the non-cash compensation recognized during the period will be adjusted accordingly. Since the fair market value of options granted to non-employees is subject to change in the future, the amount of the future compensation expense will include fair value re-measurements until the stock options are fully vested.

The Company accounts for and discloses net loss per common share in accordance with FASB ASC Topic 260 “ Earnings per Share.” Basic net loss per common share is computed by dividing net loss attributable to common stockholders by the weighted average number of common shares outstanding. Diluted net loss per common share is computed by dividing net loss attributable to common stockholders by the weighted average number of common shares that would have been outstanding during the period assuming the issuance of common shares for all potential dilutive common shares outstanding. Potential common shares consist of shares issuable upon the exercise of stock options and warrants. Because the inclusion of potential common shares would be anti-dilutive for all periods presented diluted net loss per common share is the same as basic net loss per common share.

Description of Business and Basis of Presentation (Tables)
Other Income (Expense)

Other Income (Expense)

Other income (expense) consists of the following (in thousands):

 

     For the Three
Months Ended
September 30,
2012
    For the Three
Months Ended
September 30,
2011
    For the Nine
Months Ended
September 30,
2012
    For the Nine
Months Ended
September 30,
2011
 

Change in the fair value of warrants potentially settleable in cash

   $ (262   $ (1,052   $ (11,899   $ 1,042   

Change in the fair value of contingent purchase price consideration

     (471     655       (2,019     683   

Miscellaneous other expense

     —          —          —          (2
  

 

 

   

 

 

   

 

 

   

 

 

 

Total other income (expense)

   $ (733   $ (397   $ (13,918   $ 1,723   
  

 

 

   

 

 

   

 

 

   

 

 

 
NeuVaxTM Acquisition (Tables)

The purchase price consideration and allocation of purchase price were as follows:

 

     (in 000’s)  

Calculation of allocable purchase price:

  

Fair value of shares issued at closing including escrowed shares expected to be released

   $ 6,367 (i)

Estimated value of contingent consideration

     6,460   
  

 

 

 

Total allocable purchase price

   $ 12,827   
  

 

 

 

Allocation of purchase price:

  

Cash

   $ 168   

Prepaid expenses and other current assets

     14   

Equipment and furnishings

     11   

Goodwill

     5,898   

In-process research and development

     12,864   

Accounts payable

     (931 )

Accrued expenses and other current liabilities

     (143 )

Notes payable

     (1 )

Deferred tax liability, non-current

     (5,053 )
  

 

 

 
   $ 12,827   
  

 

 

 

 

(i) The value of the Company’s common stock was based upon a per share value of $1.28, the closing price of the Company’s common stock as reported on The NASDAQ Capital Market on April 13, 2011.

The following presents the pro forma net loss and pro forma net loss per common share for the three and nine months ended September 30, 2011 (amounts in thousands, except per share data):

 

     For the Three
Months Ended
September 30, 2011
    For the Nine
Months Ended
September 30, 2011
 

Net loss from continuing operations

   $ (4,194 )   $ (8,533 )

Net loss from discontinued operations

   $ (1,641 )   $ (5,898 )

Net loss per common share, continuing operations

   $ (0.10 )   $ (0.24

Net loss per common share, discontinued operations

   $ (0.04 )   $ (0.17

Net loss per common share

   $ (0.14 )   $ (0.41 )
RXi Spin-Off (Tables)
Summary of Balance Sheet Information Related to the Net Assets Distributed in the Spin-Off

an equity distribution. Summarized balance sheet information related to the net assets distributed in the spin-off are as follows (in thousands):

 

     April 27,
2012
    December 31,
2011
 

Assets

    

Cash and cash equivalents

   $ 87      $ 556   

Other current assets

     66        783   

Equipment and furnishings

     315        355   

Liabilities

    

Accounts payable and accrued liabilities

     (1,607 )     (1,747 )

Convertible notes

     (1,000 )     (500 )

Capital lease obligations

     (20 )     (34 )
  

 

 

   

 

 

 

Net liabilities

   $ (2,159 )   $ (587 )
  

 

 

   

 

 

 
Fair Value Measurements (Tables)

The following table presents information about our assets and liabilities that are measured at fair value on a recurring basis as of September 30, 2012 and December 31, 2011, respectively, and indicates the fair value hierarchy of the valuation techniques we utilized to determine such fair value (in thousands):

 

Description    September 30,
2012
     Quoted
Prices in
Active
Markets
(Level 1)
     Significant
Other
Observable
Inputs
(Level 2)
     Unobservable
Inputs
(Level 3)
 

Assets:

           

Cash equivalents

   $ 14,746       $ 14,746       $ —         $ —     
  

 

 

    

 

 

    

 

 

    

 

 

 

Total assets

   $ 14,746       $ 14,746       $ —         $ —     
  

 

 

    

 

 

    

 

 

    

 

 

 

Liabilities:

           

Warrants potentially settleable in cash

   $ 4,904       $ —         $ 4,904       $ —     

Contingent purchase price consideration

     6,791         —           —           6,791   
  

 

 

    

 

 

    

 

 

    

 

 

 

Total liabilities

   $ 11,695       $ —         $ 4,904       $ 6,791   
  

 

 

    

 

 

    

 

 

    

 

 

 
Description    December 31,
2011
     Quoted
Prices in
Active
Markets
(Level 1)
     Significant
Other
Observable
Inputs
(Level 2)
     Unobservable
Inputs
(Level 3)
 

Assets:

           

Cash equivalents

   $ 11,433       $ 11,433       $ —         $ —     
  

 

 

    

 

 

    

 

 

    

 

 

 

Total assets

   $ 11,433       $ 11,433       $ —         $ —     
  

 

 

    

 

 

    

 

 

    

 

 

 

Liabilities:

           

Warrants potentially settleable in cash

   $ 3,746       $ —         $ 3,746       $ —     

Contingent purchase price consideration

     6,351         —           —           6,351   
  

 

 

    

 

 

    

 

 

    

 

 

 

Total liabilities

   $ 10,097       $ —         $ 3,746       $ 6,351   
  

 

 

    

 

 

    

 

 

    

 

 

 

A reconciliation of the beginning and ending Level 3 liabilities for the nine months ended September 30, 2012 is as follows (in thousands):

 

    3 Months
Ended
September 30,
2012
     9 Months
Ended
September 30,
2012
 

Balance, beginning of period

  $ 6,320       $ 6,351   

Payment of contingent purchase price consideration milestone

    —           (1,579

Changes in the estimated fair value of contingent acquisition purchase price consideration

    471         2,019   
 

 

 

    

 

 

 

Balance at September 30, 2012

  $ 6,791       $ 6,791   
 

 

 

    

 

 

 
Stock Based Compensation (Tables)

The Company is currently using the Black-Scholes option-pricing model to determine the fair value of all its option grants. For option grants in the three and nine months ended September 30, 2012 and 2011, the following assumptions were used:

 

     For the Three Months Ended September 30,     For the Nine Months Ended September 30,  
     2012     2011     2012     2011  

Weighted average risk-free interest rate

     0.85 %     1.03 %     1.06 %     1.59 %

Weighted average expected volatility

     75.35     98.94 %     75.67     103.27

Weighted average expected lives (years)

     6.25        5.34        6.13        5.49   

Weighted average expected dividend yield

     0.00 %     0.00 %     0.00 %     0.00 %

The following table summarizes stock option activity from January 1, 2012 through September 30, 2012:

 

     Total
Number of
Shares
    Weighted
Average
Exercise
Price
     Aggregate
Intrinsic
Value
 

Outstanding at January 1, 2012

     6,163,137      $ 3.03       $ —     

Granted

     1,650,000        0.92         —     

Exercised

     (11,250     0.76         10,463   

Cancelled

     (261,816     3.51         —     
  

 

 

      

Outstanding at September 30, 2012

     7,540,071      $ 2.55       $ 3,386,718   
  

 

 

      

Options exercisable at September 30, 2012

     5,535,205      $ 3.08       $ 1,928,425   
  

 

 

      
Warrants (Tables)

The following is a summary of warrant activity for the nine months ended September 30, 2012 (in thousands):

 

     April
2011
Warrants
    March
2011
Warrants
    March
2010
Warrants
    August
2009
Warrants
     Consultant
Warrants
     Total  

Warrants outstanding, January 1, 2012

     9,470        2,400        540        978         733         14,121   

Warrants issued

     —          —          —          —           400         400   

Warrants exercised

     (6,595     (1,999     (180     —           —           (8,774
  

 

 

   

 

 

   

 

 

   

 

 

    

 

 

    

 

 

 

Warrants outstanding, September 30, 2012

     2,875        401        360        978         1,133         5,747   
  

 

 

   

 

 

   

 

 

   

 

 

    

 

 

    

 

 

 

Expiration

    
 
April
2017
  
  
   
 
March
2016
  
  
   
 
March
2016
  
  
   
 
August
2014
  
  
    
 
January
2014
  
  
  

expenses as other income (expense). The fair value of the warrants is estimated using the Black-Scholes option pricing model with the following inputs:

 

     As of September 30, 2012  
     April 2011
Warrants
    March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
 

Strike price

   $ 0.65      $ 0.65      $ 2.50      $ 4.50   

Expected term

     4.56        3.43        3.50        1.80   

Volatility

     78.93     67.96     68.18     62.59

Risk free rate

     0.55     0.38     0.39     0.22
     As of December 31, 2011  
     April 2011
Warrants
    March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
 

Strike price

   $ 0.65      $ 0.65      $ 2.50      $ 4.50   

Expected term

     5.30        0.03        4.80        2.60   

Volatility

     98.91     98.91     98.91     98.91

Risk free rate

     0.83     0.02     0.83     0.31

The change in fair value of the warrant liability during the three months ended September 30, 2012 was as follows (in thousands):

 

     April 2011
Warrants
    March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
    Total  

Warrant liability, June 30, 2012

   $ 3,736      $ 1,013      $ 305      $ 175      $ 5,229   

Fair value of warrants exercised

     (25     (562     —          —          (587

Change in fair value of warrants

     286        54        (55     (23     262   
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Warrant liability, September 30, 2012

   $ 3,997      $ 505      $ 250      $ 152      $ 4,904   
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

The change in fair value of the warrant liability during the nine months ended September 30, 2012 was as follows (in thousands):

 

     April 2011
Warrants
    March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
     Total  

Warrant liability, January 1, 2012

   $ 3,154      $ 412      $ 116      $ 64       $ 3,746   

Fair value of warrants exercised

     (8,086     (2,401     (254     —           (10,741

Change in fair value of warrants

     8,929        2,494        388        88         11,899   
  

 

 

   

 

 

   

 

 

   

 

 

    

 

 

 

Warrant liability, September 30, 2012

   $ 3,997      $ 505      $ 250      $ 152       $ 4,904   
  

 

 

   

 

 

   

 

 

   

 

 

    

 

 

 

The change in fair value of the warrant liability during the three months ended September 30, 2011 was as follows (in thousands):

 

     April 2011
Warrants
    March 2011
Warrants
     March 2010
Warrants
     August 2009
Warrants
    Total  

Warrant liability, June 30, 2011

   $ 12,320      $ 1,310       $ 324       $ 300      $ 14,254   

Fair value of warrants exercised

     (80     —           —           —          (80

Change in fair value of warrants

     903        162         —           (13     1,052   
  

 

 

   

 

 

    

 

 

    

 

 

   

 

 

 

Warrant liability, September 30, 2011

   $ 13,143      $ 1,472       $ 324       $ 287      $ 15,226   
  

 

 

   

 

 

    

 

 

    

 

 

   

 

 

 

 

The change in fair value of the warrant liability during the nine months ended September 30, 2011 was as follows (in thousands):

 

     April 2011
Warrants
     March 2011
Warrants
    March 2010
Warrants
    August 2009
Warrants
    Total  

Warrant liability, January 1, 2011

   $ —         $ —        $ 1,195      $ 1,943      $ 3,138   

Fair value of warrants issued

     11,438         1,794        —          —          13,232   

Fair value of warrants exercised

     —           (102     —          —          (102

Change in fair value of warrants

     1,705         (220     (871     (1,656     (1,042
  

 

 

    

 

 

   

 

 

   

 

 

   

 

 

 

Warrant liability, September 30, 2011

   $ 13,143       $ 1,472      $ 324      $ 287      $ 15,226   
  

 

 

    

 

 

   

 

 

   

 

 

   

 

 

 
Description of Business and Basis of Presentation - Additional Information (Detail)
9 Months Ended
Sep. 30, 2012
Business And Basis Of Presentation [Line Items]
 
Date of incorporation
Apr. 03, 2006 
Description of Business and Basis of Presentation - Other Income (Expense) (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 9 Months Ended 108 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Other Income Expense [Line Items]
 
 
 
 
 
Change in the fair value of warrants potentially settleable in cash
$ (262)
$ (1,052)
$ (11,899)
$ 1,042 
 
Change in the fair value of contingent purchase price consideration
(471)
655 
(2,019)
683 
 
Miscellaneous other expense
 
 
 
(2)
 
Total other income (expense)
$ (733)
$ (397)
$ (13,918)
$ 1,723 
$ (1,859)
Recent Accounting Pronouncements - Additional Information (Detail)
9 Months Ended
Sep. 30, 2012
Summary Of Significant Accounting Policies And Recent Accounting Pronouncements [Line Items]
 
Minimum likely hood for more-likely-than-not threshold
50.00% 
NeuVaxTM - Additional Information (Detail) (USD $)
1 Months Ended 6 Months Ended 9 Months Ended
Feb. 29, 2012
Apr. 30, 2011
Sep. 30, 2012
Sep. 30, 2012
Feb. 10, 2012
Jan. 18, 2012
Dec. 31, 2011
Sep. 30, 2011
Apr. 13, 2011
Business Acquisition [Line Items]
 
 
 
 
 
 
 
 
 
Date of acquisition of Apthera Inc
 
Apr. 13, 2011 
 
 
 
 
 
 
 
Approximate shares of common stock issued to Apthera's stockholders
 
5,000,000 
 
 
 
 
 
 
 
Future contingent payments
 
 
 
 
 
 
 
 
$ 32,000,000 
Value of the company's common stock
 
 
$ 0.0001 
$ 0.0001 
 
 
$ 0.0001 
 
$ 1.28 
Estimated value of the earn-out consideration
 
 
6,500,000 
6,500,000 
 
 
 
6,460,000 
 
Contingent liability
 
 
1,000,000 
 
 
 
 
 
 
Restricted shares of common stock issued
 
 
1,315,849 
 
 
 
 
 
 
Increase in number of milestone shares on obtaining shareholder approval
 
 
 
 
 
$ 0.76 
 
 
 
Payment to the former Apthera shareholders in cash
35,016 
 
 
 
 
 
 
 
 
Payment to the former Apthera shareholders in cash at an interest factor
 
 
 
 
10.00% 
 
 
 
 
Additional other expense related to fair value of the shares on the date of issuance
 
 
 
579,000 
 
 
 
 
 
Increase in the fair value of the contingent liability
 
 
 
2,019,000 
 
 
 
 
 
Fair value of the contingent liability
 
 
6,791,000 
6,791,000 
 
 
 
 
 
Current contingent liability
 
 
$ 925,000 
$ 925,000 
 
 
 
 
 
NeuVax Acquisition - Purchase Price Consideration and Allocation of Purchase Price of Apthera (Detail) (USD $)
In Thousands, unless otherwise specified
Sep. 30, 2012
Sep. 30, 2011
Calculation of allocable purchase price:
 
 
Fair value of shares issued at closing including escrowed shares expected to be released
 
$ 6,367 
Estimated value of contingent consideration
6,500 
6,460 
Total allocable purchase price
12,827 
12,827 
Allocation of purchase price:
 
 
Cash
 
168 
Prepaid expenses and other current assets
 
14 
Equipment and furnishings
 
11 
Goodwill
 
5,898 
In-process research and development
 
12,864 
Accounts payable
 
(931)
Accrued expenses and other current liabilities
 
(143)
Notes payable
 
(1)
Deferred tax liability, non-current
 
(5,053)
Total allocable purchase price
$ 12,827 
$ 12,827 
NeuVax Acquisition - Pro Forma Net Loss and Pro Forma Net Loss Per Common Share (Detail) (USD $)
In Thousands, except Per Share data, unless otherwise specified
3 Months Ended 9 Months Ended
Sep. 30, 2011
Sep. 30, 2011
Business Acquisition [Line Items]
 
 
Net loss from continuing operations
$ (4,194)
$ (8,533)
Net loss from discontinued operations
$ (1,641)
$ (5,898)
Net loss per common share, continuing operations
$ (0.10)
$ (0.24)
Net loss per common share, discontinued operations
$ (0.04)
$ (0.17)
Net loss per common share
$ (0.14)
$ (0.41)
RXi Spin-Off - Additional Information (Detail) (USD $)
9 Months Ended 1 Months Ended 9 Months Ended
Sep. 30, 2012
Apr. 27, 2012
Dec. 31, 2011
Sep. 24, 2011
Sep. 30, 2012
Rxi [Member]
Sep. 30, 2012
Rxi [Member]
Apr. 27, 2012
Rxi [Member]
Sep. 24, 2011
Rxi [Member]
Related Party Transaction [Line Items]
 
 
 
 
 
 
 
 
Cash contribution in capital
 
 
 
$ 1,500,000 
 
 
 
 
Proceeds from Technology Revenue
45,000,000 
 
 
 
 
 
 
 
Proceeds from technology revenue under condition one
15,000,000 
 
 
 
 
 
 
 
Proceeds from technology revenue under condition two
30,000,000 
 
 
 
 
 
 
 
Minimum estimated sales
 
 
 
 
 
500,000,000 
 
 
Estimated Sales
 
 
 
 
 
1,000,000,000 
 
 
Issue of series A preferred stock
 
 
 
9,500,000 
 
 
 
 
Maximum amount of lending from investor
 
 
 
 
1,500,000 
 
 
 
Total investment
14,165,000 
 
10,112,000 
 
 
 
 
9,500,000 
Percentage of common stock shares outstanding
 
 
 
9.999% 
 
 
 
 
Percentage of as-converted common stock
 
 
 
83.00% 
 
 
8.00% 
 
Number of shares distributed to surrenders under spin-off
 
 
 
 
 
 
66,959,894 
 
Number of shares retained by company under spin-off
 
 
 
 
 
 
32,734,235 
 
Lock up period of shares under spin-off
 
 
 
 
 
1 year 
 
 
Retained price per shares under spin-off
 
 
 
 
$ 0.11 
$ 0.11 
 
 
Retained value of shares under spin-off
 
 
 
 
3,600,000 
3,600,000 
 
 
Proceeds under breach of contract
 
300,000 
 
 
 
 
 
 
Payment under breach of contract
 
 
 
 
 
 
100,000 
 
Bridge loan provided by investor
 
 
 
 
 
 
$ 1,000,000 
 
Convertible debt rate effective percentage
 
7.00% 
 
 
 
 
 
 
Convertible share conversion price one
 
$ 1,000 
 
 
 
 
 
 
Fair Value Measurements - Contingent Purchase Price Consideration, Measured at Estimated Fair Value on Recurring Basis (Detail) (USD $)
In Thousands, unless otherwise specified
Sep. 30, 2012
Jun. 30, 2012
Dec. 31, 2011
Liabilities:
 
 
 
Warrants potentially settleable in cash
$ 4,904 
 
$ 3,746 
Contingent purchase price consideration
6,791 
6,320 
6,351 
Fair Value, Measurements, Recurring [Member]
 
 
 
Assets:
 
 
 
Cash equivalents
14,746 
 
11,433 
Total assets
14,746 
 
11,433 
Liabilities:
 
 
 
Warrants potentially settleable in cash
4,904 
 
3,746 
Contingent purchase price consideration
6,791 
 
6,351 
Total liabilities
11,695 
 
10,097 
Fair Value, Measurements, Recurring [Member] |
Quoted Prices in Active Markets (Level 1) [Member]
 
 
 
Assets:
 
 
 
Cash equivalents
14,746 
 
11,433 
Total assets
14,746 
 
11,433 
Fair Value, Measurements, Recurring [Member] |
Significant Other Observable Inputs (Level 2) [Member]
 
 
 
Liabilities:
 
 
 
Warrants potentially settleable in cash
4,904 
 
3,746 
Total liabilities
4,904 
 
3,746 
Fair Value, Measurements, Recurring [Member] |
Unobservable Inputs (Level 3) [Member]
 
 
 
Liabilities:
 
 
 
Contingent purchase price consideration
6,791 
 
6,351 
Total liabilities
$ 6,791 
 
$ 6,351 
Fair Value Measurements - Reconciliation of Level 3 Liabilities (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 9 Months Ended 117 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Fair Value Measurements Of Financial Instruments [Line Items]
 
 
 
 
 
Beginning Balance Liabilities
$ 6,320 
 
$ 6,351 
 
 
Payment of a contingent purchase price consideration milestone
 
 
(1,579)
 
(1,579)
Changes in the estimated fair value of contingent acquisition purchase price consideration
471 
(655)
2,019 
(683)
 
Ending Balance Liabilities
$ 6,791 
 
$ 6,791 
 
$ 6,791 
Stock Based Compensation - Assumptions for Option Grants Issued (Detail)
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Share Based Payment Award Stock Options Valuation Assumptions [Line Items]
 
 
 
 
Weighted average risk-free interest rate
0.85% 
1.03% 
1.06% 
1.59% 
Weighted average expected volatility
75.35% 
98.94% 
75.67% 
103.27% 
Weighted average expected lives (years)
6 years 3 months 
5 years 4 months 2 days 
6 years 1 month 17 days 
5 years 5 months 27 days 
Weighted average expected dividend yield
0.00% 
0.00% 
0.00% 
0.00% 
Stock Based Compensation - Additional Information (Detail)
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Stock Based Compensation [Line Items]
 
 
 
 
Weighted Average Exercise Price, Granted
$ 1.23 
$ 0.66 
$ 0.59 
$ 0.91 
Estimated annualized forfeiture rate for options granted to employees
 
 
15.00% 
 
Estimated annualized forfeiture rate for options granted to senior management
 
 
8.00% 
 
Closing price of the Company's common stock
$ 1.78 
 
$ 1.78 
 
Stock Based Compensation - Stock Option Activity (Detail) (USD $)
9 Months Ended
Sep. 30, 2012
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
 
Stock options activity, Aggregate Intrinsic Value, Beginning Balance
   
Granted
   
Exercised
10,463 
Cancelled
   
Stock options activity, Aggregate Intrinsic Value, Ending Balance
3,386,718 
Stock options activity, Aggregate Intrinsic Value, exercisable
$ 1,928,425 
Total number of shares outstanding, Beginning Balance
6,163,137 
Stock options activity, Number of shares, Granted
1,650,000 
Stock options activity, Number of shares, Exercised
(11,250)
Stock options activity, Number of shares, Cancelled
(261,816)
Total number of shares outstanding, Ending Balance
7,540,071 
Total number of shares, exercisable
5,535,205 
Stock options activity, Weighted Average Exercise Price, Beginning balance
$ 3.03 
Stock options activity, Weighted Average Exercise Price, Granted
$ 0.92 
Stock options activity, Weighted Average Exercise Price, Exercised
$ 0.76 
Stock options activity, Weighted Average Exercise Price, Cancelled
$ 3.51 
Stock options activity, Weighted Average Exercise Price, Ending balance
$ 2.55 
Weighted Average Exercise Price, exercisable
$ 3.08 
Net Loss Per Share - Additional Information (Detail)
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Stock options [Member]
 
 
 
 
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
 
 
 
 
Shares of common stock issuable upon the exercise which were excluded from the computation of diluted earnings per share
7,540,000 
6,452,000 
7,540,000 
6,452,000 
Warrants to purchase common stock [Member]
 
 
 
 
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
 
 
 
 
Shares of common stock issuable upon the exercise which were excluded from the computation of diluted earnings per share
5,747,000 
20,051,000 
 
20,051,000 
Stockholders' Equity - Additional Information (Detail) (USD $)
1 Months Ended 9 Months Ended 117 Months Ended
Apr. 30, 2012
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Equity [Line Items]
 
 
 
 
Underwritten of shares through public offering
9,751,000 
 
 
 
Gross proceeds from underwritten public offering
$ 14,626,500 
 
 
 
Net proceeds from underwritten public offering after underwriting discount
$ 13,937,000 
$ 13,937,000 
$ 18,609,000 
$ 78,919,000 
Warrants - Schedule of stock options (Detail)
In Thousands, unless otherwise specified
9 Months Ended
Sep. 30, 2012
Warrant
Sep. 30, 2011
Warrant
Class of Warrant or Right [Line Items]
 
 
Warrants outstanding , Beginning balance
14,121 
 
Warrants issued
400,000 
13,232,000 
Warrants exercised
(8,774)
 
Warrants outstanding , Ending balance
5,747 
 
April Two Thousand Eleven Warrant [Member]
 
 
Class of Warrant or Right [Line Items]
 
 
Warrants outstanding , Beginning balance
9,470 
 
Warrants issued
   
11,438,000 
Warrants exercised
(6,595)
 
Warrants outstanding , Ending balance
2,875 
 
Expiration
Apr. 30, 2017 
 
March Two Thousand Eleven Warrant [Member]
 
 
Class of Warrant or Right [Line Items]
 
 
Warrants outstanding , Beginning balance
2,400 
 
Warrants issued
   
1,794,000 
Warrants exercised
(1,999)
 
Warrants outstanding , Ending balance
401 
 
Expiration
Mar. 31, 2016 
 
March Two Thousand Ten Warrant [Member]
 
 
Class of Warrant or Right [Line Items]
 
 
Warrants outstanding , Beginning balance
540 
 
Warrants issued
   
 
Warrants exercised
(180)
 
Warrants outstanding , Ending balance
360 
 
Expiration
Mar. 31, 2016 
 
August Two Thousand Nine Warrant [Member]
 
 
Class of Warrant or Right [Line Items]
 
 
Warrants outstanding , Beginning balance
978 
 
Warrants issued
   
 
Warrants outstanding , Ending balance
978 
 
Expiration
Aug. 31, 2014 
 
Consultant Warrants [Member]
 
 
Class of Warrant or Right [Line Items]
 
 
Warrants outstanding , Beginning balance
733 
 
Warrants issued
400,000 
 
Warrants outstanding , Ending balance
1,133 
 
Expiration
Jan. 31, 2014 
 
Warrants - Fair value of warrants is estimated using Black - Scholes option pricing model (Detail)
9 Months Ended 12 Months Ended
Sep. 30, 2012
Dec. 31, 2011
April Two Thousand Eleven Warrant [Member]
 
 
Class of Warrant or Right [Line Items]
 
 
Strike price
$ 0.65 
$ 0.65 
Expected term
4 years 6 months 22 days 
5 years 2 months 18 days 
Volatility
78.93% 
98.91% 
Risk free rate
0.55% 
0.83% 
March Two Thousand Eleven Warrant [Member]
 
 
Class of Warrant or Right [Line Items]
 
 
Strike price
$ 0.65 
$ 0.65 
Expected term
3 years 5 months 5 days 
11 days 
Volatility
67.96% 
98.91% 
Risk free rate
0.38% 
0.02% 
March Two Thousand Ten Warrant [Member]
 
 
Class of Warrant or Right [Line Items]
 
 
Strike price
$ 2.50 
$ 2.50 
Expected term
3 years 6 months 
4 years 9 months 18 days 
Volatility
68.18% 
98.91% 
Risk free rate
0.39% 
0.83% 
August Two Thousand Nine Warrant [Member]
 
 
Class of Warrant or Right [Line Items]
 
 
Strike price
$ 4.50 
$ 4.50 
Expected term
1 year 9 months 18 days 
2 years 7 months 6 days 
Volatility
62.59% 
98.91% 
Risk free rate
0.22% 
0.31% 
Warrants - Change in fair value of warrant liability (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Warrant
Sep. 30, 2011
Warrant
Class of Warrant or Right [Line Items]
 
 
 
 
Warrant liability , Beginning balance
$ 5,229 
$ 14,254 
$ 3,746 
$ 3,138 
Fair value of warrants issued
 
 
400,000 
13,232,000 
Fair value of warrants exercised
(587)
(80)
(10,741)
(102)
Change in fair value of warrants
262 
1,052 
11,899 
(1,042)
Warrant liability , Ending balance
4,904 
15,226 
4,904 
15,226 
April Two Thousand Eleven Warrant [Member]
 
 
 
 
Class of Warrant or Right [Line Items]
 
 
 
 
Warrant liability , Beginning balance
3,736 
12,320 
3,154 
 
Fair value of warrants issued
 
 
   
11,438,000 
Fair value of warrants exercised
(25)
(80)
(8,086)
 
Change in fair value of warrants
286 
903 
8,929 
1,705 
Warrant liability , Ending balance
3,997 
13,143 
3,997 
13,143 
March Two Thousand Eleven Warrant [Member]
 
 
 
 
Class of Warrant or Right [Line Items]
 
 
 
 
Warrant liability , Beginning balance
1,013 
1,310 
412 
 
Fair value of warrants issued
 
 
   
1,794,000 
Fair value of warrants exercised
(562)
 
(2,401)
(102)
Change in fair value of warrants
54 
162 
2,494 
(220)
Warrant liability , Ending balance
505 
1,472 
505 
1,472 
March Two Thousand Ten Warrant [Member]
 
 
 
 
Class of Warrant or Right [Line Items]
 
 
 
 
Warrant liability , Beginning balance
305 
324 
116 
1,195 
Fair value of warrants issued
 
 
   
 
Fair value of warrants exercised
 
 
(254)
 
Change in fair value of warrants
(55)
 
388 
(871)
Warrant liability , Ending balance
250 
324 
250 
324 
August Two Thousand Nine Warrant [Member]
 
 
 
 
Class of Warrant or Right [Line Items]
 
 
 
 
Warrant liability , Beginning balance
175 
300 
64 
1,943 
Fair value of warrants issued
 
 
   
 
Change in fair value of warrants
(23)
(13)
88 
(1,656)
Warrant liability , Ending balance
$ 152 
$ 287 
$ 152 
$ 287