FORM 3
        	UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES
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                      	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940	                      	

1. Name and Address of Reporting Person *

LECHNER IRA M	2. Date of Event Requiring Statement (MM/DD/YYYY)
3/11/2004 
	3. Issuer Name and Ticker or Trading Symbol

HALOZYME THERAPEUTICS INC [HZYM]	
(Last)        (First)        (Middle)

C/O HALOZYME THERAPEUTICS, INC., 11588 SORRENTO VALLEY ROAD, SUITE 17	4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                            _____ 10% Owner
_____ Officer (give title below)          _____ Other (specify below)	
(Street)

SAN DIEGO,, CA 92121       

(City)              (State)              (Zip)	5. If Amendment, Date Original Filed (MM/DD/YYYY)

	6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person	

Table I - Non-Derivative Securities Beneficially Owned	
1.Title of Security
(Instr. 4)	2. Amount of Securities Beneficially Owned
(Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)	4. Nature of Indirect Beneficial Ownership
(Instr. 5)	
Common Stock  	100000  	D  	 	
Common Stock  	693745  	I  	Held in the name of the Ira M. Lechner IRA Rollover dated 7-30-98.  	
Common Stock  	11465  	I  	Held in the name of Ira M. Lechner and Winifred Eileen Haag, Husband and Wife, as Community Property  	
Common Stock  	190072  	I  	Held in the name of Ira M. Lechner Charitable Remainder Trust U/A, dated December 27, 1988.  	

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)	
1. Title of Derivate Security
(Instr. 4)	2. Date Exercisable and Expiration Date
(MM/DD/YYYY)	3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)	4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)	6. Nature of Indirect Beneficial Ownership
(Instr. 5)	
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares				
Warrants to Purchase Common Stock   (1)	11/29/2001  	2/15/2005  	Common Stock  	94771  	$0.4748  	I  	Held in the name of the Ira M. Lechner IRA Rollover dated 7-30-98.  	
Warrants to Purchase Common Stock (2002 Bridge Financing)  	10/20/2003  	10/20/2007  	Common Stock  	40035  	$0.4496  	I  	Held in the name of the Ira M. Lechner IRA Rollover dated 7-30-98.  	
Warrants to Purchase Common Stock (2003 Bridge Financing)  	10/20/2003  	10/20/2007  	Common Stock  	22241  	$0.4496  	I  	Held in the name of the Ira M. Lechner Charitable Remainder Trust U/A, dated December 27, 1988.  	

Explanation of Responses:	
(  1) 	Series B Preferred Stock Financing	

Reporting Owners	
Reporting Owner Name / Address	Relationships	
	Director	10% Owner	Officer	Other	
LECHNER IRA M
C/O HALOZYME THERAPEUTICS, INC.
11588 SORRENTO VALLEY ROAD, SUITE 17
SAN DIEGO,, CA 92121	X				

Signatures		
/s/ Ira M. Lechner		3/17/2004	
** Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.	
*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).	
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).	
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.	
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.