FORM 3
        	UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES
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                      	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940	                      	

1. Name and Address of Reporting Person *

V-Sciences Investments Pte Ltd	2. Date of Event Requiring Statement (MM/DD/YYYY)
10/19/2006 
	3. Issuer Name and Ticker or Trading Symbol

VICAL INC [VICL]	
(Last)        (First)        (Middle)

60B ORCHARD ROAD, #06-18 TOWER 2, THE ATRIUM@ORCHARD	4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            ___ X ___ 10% Owner
_____ Officer (give title below)          _____ Other (specify below)	
(Street)

SINGAPORE 238891       

(City)              (State)              (Zip)	5. If Amendment, Date Original Filed (MM/DD/YYYY)

	6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person	

Table I - Non-Derivative Securities Beneficially Owned	
1.Title of Security
(Instr. 4)	2. Amount of Securities Beneficially Owned
(Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)	4. Nature of Indirect Beneficial Ownership
(Instr. 5)	
Common Shares  	4980079  	D   (1)	 	

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)	
1. Title of Derivate Security
(Instr. 4)	2. Date Exercisable and Expiration Date
(MM/DD/YYYY)	3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)	4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)	6. Nature of Indirect Beneficial Ownership
(Instr. 5)	
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares				

Explanation of Responses:	
(  1) 	Temasek Holdings (Private) Limited, is the parent of Fullerton Management Pte Ltd, which is the parent of Temasek Life Sciences Private Limited, which is the parent of V-Sciences Investments Pte Ltd (the designated filer), which directly owns the shares of common stock, $0.01 par value per share, which are the subject of this filing (the "Shares"). Because of the foregoing relationships, the direct and indirect parents of V-Sciences Investments Pte Ltd may be deemed to beneficially own the Shares.	

Reporting Owners	
Reporting Owner Name / Address	Relationships	
	Director	10% Owner	Officer	Other	
V-Sciences Investments Pte Ltd
60B ORCHARD ROAD, #06-18 TOWER 2
THE ATRIUM@ORCHARD
SINGAPORE 238891		X			
Temasek Life Sciences Private LTD
60B ORCHARD ROAD, #06-18 TOWER 2
THE ATRIUM@ORCHARD
SINGAPORE 238891		X			
Fullerton Management Pte Ltd
60B ORCHARD ROAD, #06-18 TOWER 2
THE ATRIUM@ORCHARD
SINGAPORE 238891		X			
TEMASEK HOLDINGS (PRIVATE) LTD
60B ORCHARD ROAD, #06-18 TOWER 2
THE ATRIUM@ORCHARD
SINGAPORE 238891		X			

Signatures		
V-Sciences Investments Pte Ltd, /s/ Yi Ming Syn, Director		10/29/2006	
** Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.	
*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).	
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).	
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.	
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.