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SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549

FORM 11-K

 
x	ANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934	
For the fiscal year ended December 31, 2005
 
¨	TRANSITION REPORT PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 [NO FEE REQUIRED]	
For the transition period from              to             
COMMISSION FILE NUMBER 1-1136

 
A.	Full title of the plan and the address of plan, if different from that of the issuer named below:	
BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
 
B.	Name of issuer of the securities held pursuant to the plan and the address of its principal executive office:	
BRISTOL-MYERS SQUIBB COMPANY
345 PARK AVENUE
NEW YORK, NY 10154
(212) 546-4000

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BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
FINANCIAL STATEMENTS
AND SUPPLEMENTARY INFORMATION
DECEMBER 31, 2005 AND 2004

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REQUIRED INFORMATION
 
1.	The Financial Statements and Supplemental Schedule of the Bristol-Myers Squibb Company Savings and Investment Program, prepared in accordance with the financial reporting requirements of the Employee Retirement Income Security Act of 1974, as amended.	
 
2.	Exhibits : Exhibit 23. Consent of PricewaterhouseCoopers LLP, Independent Registered Public Accounting Firm.	

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SIGNATURE
The Program
Pursuant to the requirements of the Securities Exchange Act of 1934, the Bristol-Myers Squibb Company Savings Plan Committee has duly caused this annual report to be signed on its behalf by the undersigned, hereunto duly authorized.

	 	BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM	
			
Date: June 20, 2006	 	By:	 	/s/ Andrew R. J. Bonfield	
	 		 	Andrew R. J. Bonfield
Chief Financial Officer
Chairman, Bristol-Myers Squibb
Company Savings Plan Committee	

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 BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
INDEX TO FINANCIAL STATEMENTS AND SCHEDULE
DECEMBER 31, 2005

 	  	Page No.	
Report of Independent Registered Public Accounting Firm	  	F-2	
		
Statements of Net Assets Available For Benefits –
As of December 31, 2005 and 2004	  	F-3	
		
Statements of Changes in Net Assets Available For Benefits –
For the Years Ended December 31, 2005 and 2004	  	F-4	
		
Notes to Financial Statements	  	F-5 to F-16	
		
Schedule H (Line 4i) – Schedule of Assets (Held at Year End)	  	S-1	
		
Exhibit 23 – Consent of Independent Registered Public Accounting Firm	  	E-1	
Other schedules required by Section 2520.103-10 of the Department of Labor Rules and Regulations for Reporting and Disclosure under the Employee Retirement Income Security Act of 1974 (“ERISA”) have been omitted because they are not applicable.
 
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 Report of Independent Registered Public Accounting Firm
To the Participants and Administrator of
the Bristol-Myers Squibb Company Savings
and Investment Program and the Savings
Plan Committee of Bristol-Myers Squibb Company
In our opinion, the accompanying statements of net assets available for benefits and the related statements of changes in net assets available for benefits present fairly, in all material respects, the net assets available for benefits of the Bristol-Myers Squibb Company Savings and Investment Program (the “Program”) at December 31, 2005 and 2004, and the changes in net assets available for benefits for the years then ended in conformity with accounting principles generally accepted in the United States of America. These financial statements are the responsibility of the Plan’s management. Our responsibility is to express an opinion on these financial statements based on our audits. We conducted our audits of these statements in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the accounting principles used and significant estimates made by management, and evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion.
Our audits were conducted for the purpose of forming an opinion on the basic financial statements taken as a whole. The supplemental Schedule of Assets (Held at Year End) as of December 31, 2005 is presented for the purpose of additional analysis and is not a required part of the basic financial statements but is supplementary information required by the Department of Labor’s Rules and Regulations for Reporting and Disclosure under the Employee Retirement Income Security Act of 1974. This supplemental schedule is the responsibility of the Plan’s management. The supplemental schedule has been subjected to the auditing procedures applied in the audits of the basic financial statements and, in our opinion, is fairly stated in all material respects in relation to the basic financial statements taken as a whole.

/s/ PricewaterhouseCoopers LLP	
PricewaterhouseCoopers LLP	
Philadelphia, Pennsylvania	
June 12, 2006	
 
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 BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
STATEMENTS OF NET ASSETS AVAILABLE FOR BENEFITS
AS OF DECEMBER 31, 2005 and 2004

(Dollars in Thousands)	  	2005	  	2004	
Assets:	  			  			
			
Interest in Savings Plan Master Trust	  	$	3,092,833	  	$	3,054,419	
Loans to participants	  	 	19,184	  	 	19,992	
	  	 	 	  	 	 	
Total investments	  	 	3,112,017	  	 	3,074,411	
	  	 	 	  	 	 	
Receivables:	  			  			
			
Employer contributions	  	 	1,861	  	 	1,789	
Employee contributions	  	 	4,634	  	 	4,283	
	  	 	 	  	 	 	
Total receivables	  	 	6,495	  	 	6,072	
	  	 	 	  	 	 	
Payables:	  			  			
			
Due to Bristol-Myers Squibb Company Employee Incentive Thrift Plan	  	 	1,648	  	 	—  	
Due to Bristol-Myers Squibb Puerto Rico, Inc. Savings and Investment Program	  	 	768	  	 	—  	
Due to Others	  	 	1,087	  	 	—  	
	  	 	 	  	 	 	
Total payables	  	 	3,503	  	 	—  	
	  	 	 	  	 	 	
Net Assets Available for Benefits	  	$	3,115,009	  	$	3,080,483	
	  	 	 	  	 	 	
The accompanying notes are an integral part of these financial statements.
 
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 BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
STATEMENTS OF CHANGES IN NET ASSETS AVAILABLE FOR BENEFITS
FOR THE YEARS ENDED DECEMBER 31, 2005 and 2004

(Dollars in Thousands)	  	2005	 	 	2004	 	
ADDITIONS:	  				 				
			
Employer contributions	  	$	52,319	 	 	$	52,328	 	
Employer contribution settlement	  	 	28,699	 	 	 	—  	 	
Employee contributions	  	 	158,292	 	 	 	154,475	 	
Program’s share of net investment income in Savings Plan Master Trust	  	 	88,284	 	 	 	102,756	 	
Net transfer and other income	  	 	—  	 	 	 	821	 	
	  	 	 	 	 	 	 	 	
Total additions	  	 	327,594	 	 	 	310,380	 	

DEDUCTIONS:	  				 				
			
Distributions and withdrawals	  	 	(287,072	)	 	 	(258,918	)	
Administrative expenses	  	 	(141	)	 	 	(21	)	
Net transfer	  	 	(5,855	)	 	 	—  	 	
	  	 	 	 	 	 	 	 	
Total deductions	  	 	(293,068	)	 	 	(258,939	)	
	  	 	 	 	 	 	 	 	
Net additions	  	 	34,526	 	 	 	51,441	 	
			
NET ASSETS AVAILABLE FOR BENEFITS:	  				 				
			
Beginning of Year	  	 	3,080,483	 	 	 	3,029,042	 	
	  	 	 	 	 	 	 	 	
End of Year	  	$	3,115,009	 	 	$	3,080,483	 	
	  	 	 	 	 	 	 	 	
The accompanying notes are an integral part of these financial statements.
 
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 BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 1 – DESCRIPTION OF PLAN
General
The Bristol-Myers Company Savings Plan (the Savings Plan) became effective on January 1, 1971 and was amended effective May 3, 1982 and designated as the Bristol-Myers Company Savings and Investment Program (the Savings Program). The Savings Program consisted of Part I, the Savings Plan and Part II, the Bristol-Myers Company Pre-Tax Investment Plan (the Pre-Tax Plan), providing employees with a choice to participate on either an after-tax or a pre-tax basis or a combination of both. On October 4, 1989, Squibb Corporation merged with a subsidiary of Bristol-Myers Company and Bristol-Myers Company changed its name to Bristol-Myers Squibb Company (the Company). Effective October 4, 1989, the name of the Savings Program was changed to the Bristol-Myers Squibb Company Savings and Investment Program.
Effective January 1, 1991, the Savings Plan and the Pre-Tax Plan were amended and consolidated into a single plan, the Bristol-Myers Squibb Company Savings and Investment Program (the Program). The Program eliminated the Part I and Part II distinction while maintaining after-tax and pre-tax options.
Effective October 1, 1994, the Program ceased operating within the Bristol-Myers Squibb Company Master Trust and began operating within the Bristol-Myers Squibb Company Savings Plan Master Trust (the Savings Plan Master Trust) maintained by Fidelity Investments (Fidelity). The assets of the Program were commingled within the Savings Plan Master Trust with the assets of the Bristol-Myers Squibb Company Employee Incentive Thrift Plan (the Thrift Plan).
On April 1, 1999, the Bristol-Myers Squibb Puerto Rico, Inc. Savings and Investment Program (the Puerto Rico Program) assets were transferred from Northern Trust to Fidelity and began operating within the Savings Plan Master Trust. The assets of the Program were then combined within the Savings Plan Master Trust with the assets of the Thrift Plan and the Puerto Rico Program.
The Savings Plan Master Trust Statement, presented in Note 6, includes the interests of the Program, the Thrift Plan and the Puerto Rico Program.
The Bristol-Myers Squibb Company Savings Plan Committee (the Committee) is the Administrator of the Program and named fiduciary for Program assets.
Effective March 1, 2003, the Program was amended to eliminate the six-month waiting period for new entrants to the Program. Eligible employees may participate in the Program following their date of hire, although the company matching contributions do not begin until an eligible employee has attained six months of service as prescribed by the Program.
Contributions
In general, any employee who meets certain service requirements, as defined in Article II, Section 2.1 of the Program Document, is eligible to participate in the Program. An employee electing to participate in the Program can elect to contribute up to 25% of his or her Annual Benefit Salary or Wages (as defined in the Program) on an after-tax basis or to reduce his or her compensation by up to 25%, and have such amount contributed on his or her behalf on a pre-tax basis subject to applicable limitations. Participants may also elect a combination of contributions up to a combined total, both on an after-tax and pre-tax basis, of 25% subject to applicable
 
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BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 1 – DESCRIPTION OF PLAN (Continued)
limitations. The Company contributes a matching contribution of 75% for each dollar that the participant contributes, whether the contributions are made on a pre-tax or after-tax basis, of the first 6% of the participant’s pay.
Contributions of participants and the Company are remitted to Fidelity on a bi-weekly basis and are recorded on an accrual basis. All investment decisions are self directed by participants. During the years ended December 31, 2005 and 2004 participant contributions were invested in any one or more of the following funds which comprise the Savings Plan Master Trust: Company Stock Fund, Fixed Income Fund, Fidelity Select Equity Small Capitalization Collective Trust Fund, Fidelity Equity-Income Fund, Fidelity Growth Company Fund, Fidelity U.S. Bond Index Fund, Fidelity U.S. Equity Index Commingled Pool, Fidelity U.S. Equity Index Commingled Pool Class 2, Fidelity Puritan Fund, Fidelity Retirement Money Market Portfolio, Dreyfus Appreciation Fund, Inc., Managers Special Equity Fund, Vanguard Total International Stock Index Fund, Northern Trust Global Investments Russell 2000 Equity Index Fund and American Funds Euro Pacific Growth Fund – Class R5. The Fidelity Select Equity Small Capitalization Collective Trust Fund was removed from the Program and replaced by the Northern Trust Daily Russell 2000 Equity Index Fund effective July 1, 2004. The classes of shares were switched for the Fidelity U.S. Equity Index Commingled Pool on January 31, 2005 and the name was modified to reflect the share conversion to the Fidelity U.S. Equity Index Commingled Pool Class 2.
Prior to March 1, 2003, company matching contributions were automatically invested in the Company Stock Fund. These contributions could not be transferred out of the Company Stock Fund unless the participant was 55 years of age or older. Effective March 1, 2003, the Program was amended to eliminate the requirement that company matching contributions be invested in the Company Stock Fund until age 55. Employees may now invest prior and future company matching contributions in any of the funds available under the Program. Company matching contributions, invested as indicated by the participant in any one or equally in any two or more of the funds, made to the Program prior to the January 1, 1991 merger of the Squibb Corporation Incentive Savings and Stock Ownership Plan, are also transferable among the investment funds. Effective as of January 1, 2002, the Company Stock Fund became an Employee Stock Ownership Plan or ESOP.
The Program was amended to comply with the applicable provisions of the following Federal tax laws (1997-2005):
 
•	 	The General Agreement on Tariffs and Trade 1994 (GATT)	
 
•	 	The Uniformed Services Employment and Reemployment Rights Act of 1994 (USERRA)	
 
•	 	The Small Business Job Protections Act of 1996 (SBJPA)	
 
•	 	The Taxpayer Relief Act of 1997 (TRA’97)	
 
•	 	The Internal Revenue Service (IRS) Restructuring and Reform Act of 1998 (RRA ’98), and	
 
•	 	The Economic Growth and Tax Relief Reconciliation Act of 2001 (EGTRRA) legislation.	
 
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BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 1 – DESCRIPTION OF PLAN (Continued)
The statutes listed above, with the exception of EGTRRA, are collectively referred to as GUST.
As of July 1, 2002, the Program was amended to allow for catch up contributions for eligible participants who were 50 years of age or older. The catch-up contribution is intended to give employees who are approaching retirement age the opportunity to make additional pre-tax contributions over the applicable IRS and Program limits. Generally, if an eligible employee’s contribution rate is at 25%, such contributions exceed IRS applicable limits and he or she satisfies the age requirement, then that employee may make catch-up contributions. The catch-up contribution itself is limited to $2 thousand in 2003 and will increase in thousand dollar increments to $5 thousand in 2006. Thereafter, the catch-up contribution limit will be indexed for inflation. There is no Company match on catch-up contributions.
Savings Plan Master Trust Investments
Company Stock Fund – Consists primarily of shares of common stock of Bristol-Myers Squibb Company, which are registered for the purpose of the Program with the United States Securities and Exchange Commission. From time to time, the Program may invest in U.S. Government obligations or other investments of a short-term nature, which will ultimately be used for the purchase of shares of Common Stock of Bristol-Myers Squibb Company.
Fixed Income Fund – Consists primarily of a group of annuity contracts issued by various insurance companies to the trustee of the Program under which the insurance companies provide a guarantee of principal and credit interest at a guaranteed rate. All contracts pay interest on a net basis. Contracts with John Hancock Mutual Life Insurance Company, Metropolitan Life Insurance Company, New York Life Insurance Company, Principal Mutual Life Insurance Company, Prudential Life Insurance Company, Sun America Life Insurance Company and the Travelers Insurance Co. were in place at December 31, 2005.
From time to time, the Program may invest in obligations of the U.S. Government or its agencies, bank investment contracts, other investments of a short-term nature and/or investments in qualified commingled trust Funds managed by the trustee for the investment of funds of profit sharing and savings plans and programs.
At any point in time this fund’s average yield will be a combined rate based upon the balances and the interest rates of the investments which comprise the fund, and depend on the amount of contributions invested in the fund, the amounts withdrawn from the fund and the amounts transferred to and from the fund. The fund’s average yield is measured by investment performance using general market reporting methods. The average yield of the Fixed Income Fund for the years ended December 31, 2005 and 2004 was 5.0% and 5.3%, respectively. The crediting interest rate of the Fixed Income Fund at December 31, 2005 and 2004 was 4.9% and 5.0%, respectively. The crediting interest rate at any date is the weighted average of the yields on the individual contracts and other investments in the Fixed Income Fund on that date.
 
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BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 1 – DESCRIPTION OF PLAN (Continued)
Fidelity Select Equity Small Capitalization Collective Trust Fund – Seeks investment results that exceed the return of the Russell 2000 Index while maintaining a portfolio with risk characteristics similar to the Index. This fund was discontinued effective June 30, 2004 and remaining balances were transferred to the Northern Global Trust Investments Russell 2000 Equity Index Fund.
Northern Trust Daily Russell 2000 Equity Index Fund – Seeks investment results that approximate the overall performance of common stocks included in the Russell 2000 Index.
American Funds EuroPacific Growth Fund - Class R5 – Seeks to provide capital appreciation through investment in international equities.
Fidelity Equity-Income Fund – Seeks to provide a reasonable income. In pursuing this objective, the fund will also consider the potential for capital appreciation. The fund seeks to provide a yield that exceeds the composite yield of the Standard & Poor’s (S&P) 500 Index.
Fidelity Growth Company Fund – Seeks to provide capital appreciation.
Fidelity U.S. Bond Index Fund – Seeks to provide investment results that correspond to the total return of the bonds in the Lehman Brothers Aggregate Bond Index.
Fidelity Puritan Fund – Seeks to provide income and capital growth consistent with reasonable risk.
Fidelity Retirement Money Market Portfolio – Seeks to provide a high level of current income that is consistent with the preservation of capital and liquidity.
Fidelity U.S. Equity Index Commingled Pool – Seeks to approximate the composition and the total return on the S&P 500 Index.
Fidelity U.S. Equity Index Commingled Pool - Class 2 – Seeks to approximate the composition and the total return on the S&P 500 Index.
Dreyfus Appreciation Fund, Inc. – Seeks to increase the value of investment over the long-term through capital growth. Current income is a secondary objective of this fund.
Managers Special Equity Fund – Seeks to provide capital appreciation through investments in small and medium sized companies.
Vanguard Total International Stock Index Fund - Investor Class – Seeks to approximate the composition and total return of well known international stock indices.
 
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BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 1 – DESCRIPTION OF PLAN (Continued)
Withdrawals
While remaining in employment, a participant may withdraw all or part of the value attributable to contributions made, subject to certain restrictions of the Program and excise taxes imposed by the Internal Revenue Code.
Vesting
A participant vests in Company contributions at the rate of 20% for each year of qualifying service so that after five years of qualifying service he or she is 100% vested. Upon death or normal retirement, a participant will become 100% vested in Company contributions regardless of his or her years of qualifying service. If a participant leaves the Company before becoming fully vested, the unvested portion of the Company contributions are forfeited and returned to the Company (See Note 3 for further discussions on forfeitures). Participants who return to work for the Company who were partially or fully vested will be reinstated to their previous level of vesting and may immediately enroll in the Program. A participant is always 100% vested in the amounts attributed to their own contributions – pre-tax, after-tax, rollover contributions from other plans and catch-up contributions.
Loans
While remaining in employment, a participant may request a loan from the Program. The amount of the loan may not exceed the lesser of (1) 50% of the participant’s entire vested interest under the Program, determined as of the valuation date, or (2) fifty thousand dollars less the highest outstanding loan balance during the previous twelve months.
Termination of Employment
Upon the termination of a participant’s employment, the participant, or in the event of his or her death, the participant’s spouse or designated beneficiary, may, under varying circumstances, receive (1) a lump sum payment, (2) installment payments over a period not to exceed the joint life expectancy of the participant and the participant’s spouse (five years if payment is by reason of death) or (3) an annuity for employees hired prior to October 1, 1994. In each case the payment will be based on the vested value in the respective funds allocated to the participant.
Net Transfer
A participant’s account may be transferred to or from another savings plan within the Company if their employment status changes such that they become eligible for a different plan. A participant’s account could also be transferred to another company’s savings plan if required under the terms of a divestiture of a business unit. New accounts could be transferred in from another company’s savings plan, if required under the terms of an acquisition of a new company.
 
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BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 2 – ACCOUNTING POLICIES
Valuation
Valuation of investments of the Program represents the Program’s allocable portion of the Savings Plan Master Trust’s investments. The Savings Plan Master Trust’s investment valuation policies are as follows:
The Company Stock are valued at the last reported sales price at the end of the year or, if there was not a sale that day, the last reported bid price. Common/collective trust funds are valued at the last reported bid price at the end of the year. Fixed income and money market instruments are valued at cost plus interest earned, which approximates their respective fair values. Shares of the Fidelity mutual funds and other retail mutual funds are valued at quoted market prices which represent the net asset value of shares held by the Program at year end. Investments in guaranteed investment contracts are reported at contract value by the insurance companies. The value of outstanding participant loans is determined based on the outstanding principal balance as of the last day of the Program Year, which approximates fair value.
Use of Estimates
The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make significant estimates and assumptions that affect the reported amounts of assets and liabilities and disclosures of contingent assets and liabilities at the date of the financial statements and the reported amounts of additions and deductions to the net assets available for benefits during the reporting period. Actual results could differ from those estimates.
Risks and Uncertainties
The Program provides for various investment options in funds that can invest in a combination of stocks, bonds, fixed income securities, mutual funds, and other investment securities. Investment securities are exposed to various risks, such as interest rate, market and credit. Due to the level of risk associated with certain investment securities and the level of uncertainty related to changes in the value of investment securities, it is at least reasonably possible that changes in risks in the near term could materially affect participants’ account balances and the amounts reported in the Statement of Net Assets Available for Benefits and the Statement of Changes in Net Assets Available for Benefits.
Payment of Benefits
Benefits are recorded when paid.
Income, Expenses and Realized and Unrealized Gains and Losses on Securities
Interest, dividends, and realized and unrealized gains and losses earned from participation in the Savings Plan Master Trust are allocated to the Program based upon participants’ account balances and activity. This investment activity is presented on a net basis on the Statement of Changes in Net Assets Available for Benefits as the Program’s share of net investment income in the Savings Plan Master Trust.
 
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BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 2 – ACCOUNTING POLICIES (Continued)
Interest is accrued by the Savings Plan Master Trust as earned, and dividends are recorded on the ex-dividend date.
Purchases and sales of securities are recorded by the Savings Plan Master Trust on a trade-date basis. Realized gains and losses for security transactions are reported using the average cost method. Realized and unrealized gains and losses are included in net appreciation / depreciation in the fair value of investments in the Statement of Changes in Net Assets Available for Benefits .
All expenses incurred by the Program, other than investment management and trustee fees, which are paid from each fund’s assets, are paid by the Company.
NOTE 3 – TERMINATION FORFEITURES
Forfeitures of amounts contributed by the Company due to terminations, net of amounts reinstated, are used to reduce future Company contributions. Forfeitures are also used to pay certain plan expenses. Forfeitures for the years ended December 31, 2005 and 2004 were $965 thousand and $1.0 million, respectively.
NOTE 4 – TAX STATUS OF THE PROGRAM
In the Program’s latest determination letter dated July 8, 2003, the IRS stated that the Program, as then designed, was in compliance with the applicable requirements of the Internal Revenue Code. Although the Program has been amended since receiving the determination letter, counsel believes that the Program is qualified and the related Trust is tax-exempt as of December 31, 2005 and 2004.
Under present federal income tax laws and regulations, a participant will not be subject to federal income taxes on the contributions by the employing company, or on the interest, dividends or profits on the sale of securities received by the trustee until the participant’s account is distributed to the participant.
NOTE 5 – TERMINATION OF THE PROGRAM
Although the Company has not expressed any intent to do so, it has the right to discontinue its contributions and to terminate the Program in accordance with the provisions of the Employee Retirement Income Security Act of 1974 (ERISA). If the Program is terminated, the interest of each participant in all funds will vest immediately. In accordance with Program provisions, the Company has the right to amend or replace the Program for any reason.
 
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BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 6 – MASTER TRUST
The Program’s share of the Savings Plan Master Trust’s net assets and investment activities is based upon the total of each individual participant’s share of the Savings Plan Master Trust. The Program’s approximate share of the net assets of the Savings Plan Master Trust at December 31, 2005 and 2004 was 96%.
At December 31, 2005 and 2004, the Statements of Net Assets Available for Benefits of the Savings Plan Master Trust were as follows:

  	  	2005	  	2004	
(Dollars in Thousands)	  	Cost	  	Market
Value	  	Cost	  	Market
Value	
Assets:	  			  			  			  			
					
Investments at Fair Value:	  			  			  			  			
*Company Stock Fund Bristol-Myers Squibb Company Common Stock	  	$	865,113	  	$	794,252	  	$	905,972	  	$	924,115	
*Fidelity Management Trust Company Institutional Cash Portfolio	  	 	6,311	  	 	6,311	  	 	7,924	  	 	7,924	
Northern Trust Global Investments Russell 2000 Equity Index Fund	  	 	106,044	  	 	120,599	  	 	104,569	  	 	115,665	
*Fidelity Puritan Fund	  	 	67,016	  	 	69,133	  	 	53,825	  	 	57,301	
*Fidelity Equity-Income Fund	  	 	195,303	  	 	215,095	  	 	182,302	  	 	204,890	
*Fidelity Growth Company Fund	  	 	301,927	  	 	365,640	  	 	308,806	  	 	333,671	
*Fidelity Retirement Money Market Portfolio	  	 	139,160	  	 	139,160	  	 	110,542	  	 	110,542	
*Fidelity U.S. Bond Index Fund	  	 	105,219	  	 	105,367	  	 	101,522	  	 	104,120	
*Fidelity U.S. Equity Index Commingled Pool	  	 	—  	  	 	—  	  	 	337,783	  	 	357,980	
*Fidelity U.S. Equity Index Commingled Pool - Class 2	  	 	318,412	  	 	341,499	  	 	—  	  	 	—  	
Dreyfus Appreciation Fund, Inc.	  	 	51,716	  	 	54,458	  	 	45,200	  	 	47,194	
Managers Special Equity Fund	  	 	51,399	  	 	54,096	  	 	36,377	  	 	42,522	
Vanguard Total International Stock Index Fund	  	 	54,213	  	 	63,773	  	 	29,232	  	 	33,651	
American Funds EuroPacfic Growth Fund - Class R5	  	 	39,677	  	 	43,606	  	 	9,053	  	 	9,803	
					
Fixed Income Fund at Contract Value:	  			  			  			  			
Group Annuity Contracts, New York Life Insurance Company with 2005 interest rates ranging from 4.06% to 6.83% per annum (p.a), varying maturity dates	  	 	279,578	  	 	279,578	  	 	294,659	  	 	294,659	
Group Annuity Contracts, Metropolitan Life Insurance Company with 2005 interest rates ranging from 3.84% to 4.75% p.a, varying maturity dates	  	 	74,962	  	 	74,962	  	 	46,592	  	 	46,592	
SunAmerica Life Insurance with a 2005 interest at 4.53% p.a, maturing in 2009	  	 	46,182	  	 	46,182	  	 	44,181	  	 	44,181	
Group Annuity Contracts, Prudential Life Insurance Company with 2005 interest rates ranging from 4.09% to 4.18% p.a, varying maturity dates	  	 	38,408	  	 	38,408	  	 	33,211	  	 	33,211	
Group Annuity Contracts, Principal Mutual Life Insurance Company with 2005 interest rates ranging from 4.75% to 6.55% p.a, varying maturity dates	  	 	117,524	  	 	117,524	  	 	164,277	  	 	164,277	
Group Annuity Contract, John Hancock Mutual Life Insurance Company with 2005 interest rates ranging from 4.03% to 7.47% p.a, varying maturity dates	  	 	165,043	  	 	165,043	  	 	157,612	  	 	157,612	
Group Annuity Contract, Travelers Insurance Co. with 2005 interest rates ranging from 2.98% to 4.04% p.a, varying maturity dates	  	 	90,361	  	 	90,361	  	 	65,850	  	 	65,850	
					
Fixed Income Fund at Fair Value:	  			  			  			  			
*Fidelity Institutional Cash Portfolio Money Market	  	 	30,945	  	 	30,945	  	 	24,245	  	 	24,245	
	  	 	 	  	 	 	  	 	 	  	 	 	
Total Investments	  	 	3,144,513	  	 	3,215,992	  	 	3,063,734	  	 	3,180,005	
					
Dividends Receivable	  	 	—  	  	 	9,650	  	 	—  	  	 	10,089	
	  	 	 	  	 	 	  	 	 	  	 	 	
Net Assets	  	$	3,144,513	  	$	3,225,642	  	$	3,063,734	  	$	3,190,094	

*	Denotes a party-in-interest to the Program.	
 
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Table of Contents
BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 6 – MASTER TRUST (Continued)
The total investment income of the Savings Plan Master Trust for the years ended December 31, 2005 and 2004 were as follows:

(Dollars in Thousands)	  	2005	 	 	2004	 	
Investment income, net:	  				 				
			
Interest income	  	$	50,177	 	 	$	49,661	 	
Dividend income	  	 	61,232	 	 	 	51,700	 	
Net (depreciation) / appreciation in fair value of investments	  	 	(24,373	)	 	 	(436	)	
	  	 	 	 	 	 	 	 	
Total Investment income	  	$	87,036	 	 	$	100,925	 	
	  	 	 	 	 	 	 	 	
The net depreciation in the fair value of the Savings Plan Master Trust investments by fund for the years ended December 31, 2005 and 2004 were as follows:

 (Dollars in Thousands)	  	2005	 	 	2004	 	
Company Stock Fund	  	$	(94,491	)	 	$	(113,383	)	
Fidelity Puritan Fund	  	 	(721	)	 	 	1,335	 	
Fidelity Equity-Income Fund	  	 	(68	)	 	 	11,229	 	
Fidelity Growth Company Fund	  	 	42,555	 	 	 	35,559	 	
Fidelity U.S. Bond Index Fund	  	 	(2,342	)	 	 	(599	)	
Fidelity U.S. Equity Index Commingled Pool	  	 	(8,800	)	 	 	35,201	 	
Fidelity U.S. Equity Index Commingled Pool - Class 2	  	 	24,881	 	 	 	—  	 	
Dreyfus Appreciation Fund, Inc.	  	 	1,278	 	 	 	1,786	 	
Fidelity Select Equity Small Capitalization Collective Trust Fund	  	 	—  	 	 	 	8,403	 	
Managers Special Equity Fund	  	 	(1,933	)	 	 	4,704	 	
Vanguard Total International Stock Index Fund	  	 	6,638	 	 	 	3,788	 	
Northern Trust Daily Russell 2000 Equity Index Fund	  	 	5,188	 	 	 	10,773	 	
American Funds EuroPacific Growth Fund - Class R5	  	 	3,442	 	 	 	768	 	
	  	 	 	 	 	 	 	 	
	  	$	(24,373	)	 	$	(436	)	

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Table of Contents
BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 7 – ERISA LITIGATION
In December 2002 and the first quarter of 2003, the Company and others were named as defendants in five class actions brought under ERISA in the U.S. District Courts for the Southern District of New York and the District of New Jersey. These actions were consolidated in the Southern District of New York under the caption In re Bristol-Myers Squibb Co. ERISA Litigation , 02 CV 10129 (LAP). An Amended Consolidated Complaint was served on August 18, 2003. A Second Amended Consolidated Complaint was filed on May 27, 2005. The Second Amended Consolidated Complaint was brought on behalf of four named plaintiffs and a putative class consisting of all participants in, or beneficiaries of, the Program at any time between January 1, 1999 and March 10, 2003 whose accounts included investment in the Company stock. The named defendants were the Company, the Committee, thirteen individuals who presently serve on the Committee or who served on the Committee in the recent past, Charles A. Heimbold, Jr. and Peter R. Dolan (the past and present Chief Executive Officers, respectively, of the Company). The Second Amended Consolidated Complaint generally alleged that the defendants breached their fiduciary duties under ERISA during the class period by, among other things, imprudently investing assets of the Program in the Company stock; misrepresenting and failing to disclose truthful and adequate information about the Company stock as a Program investment; and operating under conflicts of interest. In addition, all defendants except Heimbold and Dolan were alleged to have engaged in transactions prohibited under ERISA by causing the Program to acquire Company stock, and the Company, Heimbold and Dolan were alleged to have failed to monitor the other Program fiduciaries. These ERISA claims were predicated upon factual allegations concerning, among other things: the safety, efficacy and commercial viability of a Company product; the Company’s sales incentives to certain wholesalers and the inventory levels of those wholesalers; and alleged certain anticompetitive behavior.
On June 6, 2005, counsel for plaintiffs and the Company entered into a Stipulation and Agreement of Settlement (Settlement). The U.S. District Court for the Southern District of New York preliminarily approved the Settlement on June 22, 2005. On October 12, 2005, the Court conducted a Fairness Hearing, granted final approval of the Settlement and awarded attorneys’ fees totaling $8.7 million. The Settlement provides for certification, for Settlement purposes only, of a class consisting of all persons who were participants in, or beneficiaries of, (i) the Program; (ii) the Puerto Rico Program; and (iii) the Thrift Plan (collectively, the Qualified Plans), at any time between January 1, 1999 and March 10, 2003 and whose accounts in such plans included investments in the Bristol-Myers Squibb Company Stock Fund (excluding the individual defendants). The Settlement provides that the Company pay to the Savings Plan Master Trust $41.2 million less plaintiffs’ attorneys’ fees, settlement administration costs and $5 thousand to each of the four named plaintiffs (the Net Settlement Amount). The Net Settlement Amount of $32.2 million was paid to the Savings Plan Master Trust on November 21, 2005. The plaintiffs’ attorneys’ fees and the payments to the named plaintiffs were made on November 29, 2005. The settlement administration costs were $314 thousand. The distribution of the proceeds of the Settlement to class members was made on March 8, 2006 in accordance with the plan of allocation that was approved by the Court in October 2005. The plan of allocation included a certain amount of Settlement proceeds being transferred to the Zimmer Holdings, Inc. Savings and Investment Program, Zimmer Holdings Inc. Puerto Rico Savings and Investment Program, and the Matrix Plan through the
 
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Table of Contents
BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 7 – ERISA LITIGATION (Continued)
L’Oreal Savings Plan. The allocation of the Net Settlement Amount broken down by plan is as follows: the Program $28.7 million; the Thrift Plan $1.6 million; the Puerto Rico Program $759 thousand; Zimmer Holdings, Inc. Savings and Investment Program $937 thousand; Zimmer Holdings Inc. Puerto Rico Savings and Investment Program $27 thousand; and Matrix Plan via L’Oreal Savings Plan $111 thousand. The Net Settlement Amount was invested in the Fidelity Retirement Money Market Fund from November 21, 2005 to March 8, 2006. The interest earned on the Net Settlement Amount was approximately $385 thousand (the “Interest”) and was distributed to the class members on March 15, 2006. The allocation of the Interest broken down by plan is as follows: the Program $344 thousand; the Thrift Plan $20 thousand; the Puerto Rico Program $9 thousand; Zimmer Holdings, Inc. Savings and Investment Program $10 thousand; and Matrix Plan via L’Oreal Savings Plan $1 thousand. In addition, the Company agreed that (i) no proceeds that the Qualified Plans may receive from In re Bristol-Myers Squibb Co. Secur. Litig. , Master File No. 02-CV-2251 (LAP) (the Securities Litigation) would be used to offset any monies paid pursuant to the Settlement, (ii) there would be no restriction to the participants’ ability to diversify their matching contributions under the Qualified Plans for at least five years from the Settlement’s effective date, (iii) it would re-notify current participants in the Qualified Plans about the fact that they can designate the Qualified Plan fund into which their Company matching funds will be invested, and (iv) it would make an educational program concerning diversification of investments available to Qualified Plan participants, and would keep that or a similar program in place for at least five years. No employee benefit plan was a named defendant in the litigation, and no costs incurred with respect to the litigation have been borne directly by any employee benefit plan. The Net Settlement Amount of $32.2 million that was paid to the Savings Plan Master Trust on November 21, 2005 is reflected in the accompanying financial statements, and the allocation of the Net Settlement Amount to the other benefit plans referenced above and the interest on the $32.2 million are recorded as payables in the accompanying financial statements.
NOTE 8 – RELATED PARTY TRANSACTIONS
Certain Program investments are shares in registered mutual funds or units in pooled investment funds managed by affiliates of Fidelity Management Trust Company (Fidelity Trust). Fidelity Trust is the trustee as defined by the Program. The transactions involving the registered mutual funds are exempt party-in-interest transactions pursuant to the Department of Labor Class Exemption 77-4 and the transactions involving the pooled investment funds are exempt party-in-interest transactions pursuant to Section 408(b)(8) of ERISA. The Program also invests in shares of the Company. The Company is the program sponsor and, therefore, these transactions qualify as exempt party-in-interest transactions. In addition, certain Program participants borrowed from the Program. As of December 31, 2005 and 2004, the outstanding loans of the Program participants were $19.2 million and $20.0 million, respectively, with interest rates ranging from 5.00% to 12.50% and varying maturity dates. Program participants are a party-in-interest to the Program.
 
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Table of Contents
BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
NOTES TO FINANCIAL STATEMENTS
NOTE 9 – DIVESTITURES
In February 2004, the Company completed the divestiture of its Adult Nutritional business to Novartis AG (Novartis). There was an asset transfer of $1.6 million from the Program to the Novartis U.S. Savings Plan on March 31, 2004 for 24 employees who voluntarily transferred their assets. The remaining terminated employees elected to leave their assets in the Program.
In May 2005, the Company completed the divestiture of its Oncology Therapeutics Network to One Equity Partners LLC. There was an asset transfer of $3.8 million from the Program to a Savings Program maintained by One Equity Partners LLC for 105 employees who voluntarily transferred their assets. The remaining terminated employees elected to leave their assets in the Program.
The sale of the Buffalo Technical Operations facilities to Contract Pharmaceuticals Limited closed on August 25, 2005. $1.8 million was transferred to the buyer’s plan on September 16, 2005 for 61 employees who processed a “Voluntary Elective Transfer” through the Program.
The sale of the Consumer Medicines business to Novartis closed on August 31, 2005. Four employees elected the “Voluntary Elective Transfer”. On September 30, 2005, $126 thousand was transferred from the Program to the buyer’s plan.
NOTE 10 – SUBSEQUENT EVENTS
The Net Settlement Amount of $32.2 million and the interest earned thereon from November 21, 2005 to March 8, 2006, totaling $385 thousand were distributed to class members of the ERISA class action settlement referenced in Note 7 above on March 8 and March 15, 2006, respectively. See Note 7 above for further details describing these events.
 
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Table of Contents
 SCHEDULE H (Line 4i)
BRISTOL-MYERS SQUIBB COMPANY
SAVINGS AND INVESTMENT PROGRAM
SCHEDULE OF ASSETS (HELD AT YEAR END)
DECEMBER 31, 2005
(IN THOUSANDS)

Identity of issue,
borrower, lessor
or similar party	  	Description of investment including maturity date,
rate of interest, collateral, par or maturity value	  	Cost Value	  	Current Value	
* Program participant	  	Participant loans, with varying maturity dates	  		  	$	19,184	
				
	  	Interest rates: 5.00% to 12.50%	  		  			

*	Denotes a party-in-interest to the Program.	
 
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 EXHIBIT 23
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in the Registration Statement on Form S-8: (No. 33-44788, 333-02873 and 333-107414) of Bristol-Myers Squibb Company of our report dated June 12, 2006 relating to the financial statements of Bristol-Myers Squibb Company Savings and Investment Program, which appears in this Form 11-K.

/s/ PricewaterhouseCoopers LLP	
PricewaterhouseCoopers LLP	
Philadelphia, Pennsylvania	
June 22, 2006	
 
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